ENSDARG00000075682


Danio rerio

Features
Gene ID: ENSDARG00000075682
  
Biological name :orc6
  
Synonyms : orc6 / origin recognition complex, subunit 6
  
Possible biological names infered from orthology : Q9Y5N6
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 41812190
Gene end: 41826318
  
Corresponding Affymetrix probe sets: Dr.24945.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000143032
Ensembl peptide - ENSDARP00000143082
Ensembl peptide - ENSDARP00000143039
Ensembl peptide - ENSDARP00000101426
NCBI entrez gene - 324256     See in Manteia.
swissprot - A0A1L1QZG1
swissprot - A0A1L1QZC2
swissprot - Q6ZM36
ZFIN ID - ZDB-GENE-030131-2976
Ensembl - ENSDARG00000075682
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ORC6ENSGALG00000004342Gallus gallus
 ORC6ENSG00000091651Homo sapiens
 Orc6ENSMUSG00000031697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008721  Origin recognition complex, subunit 6
 IPR020529  Origin recognition complex, subunit 6, metazoa/plant


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IBA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003688 DNA replication origin binding IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008805 orc3 / origin recognition complex, subunit 3 / Q9JK30* / Q9UBD5*  / reaction
 ENSDARG00000021579 orc5 / origin recognition complex, subunit 5 / O43913* / Q9WUV0*  / reaction
 ENSDARG00000039217 orc1 / origin recognition complex, subunit 1 / Q13415* / Q9Z1N2*  / reaction
 ENSDARG00000101161 orc4 / origin recognition complex, subunit 4 / O43929*  / reaction






 

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