ENSDARG00000021579


Danio rerio

Features
Gene ID: ENSDARG00000021579
  
Biological name :orc5
  
Synonyms : orc5 / origin recognition complex, subunit 5
  
Possible biological names infered from orthology : O43913 / Q9WUV0
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 22353465
Gene end: 22363709
  
Corresponding Affymetrix probe sets: Dr.17944.1.S1_at (Zebrafish Array)   NM_213198_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000033056
NCBI entrez gene - 406479     See in Manteia.
RefSeq - NM_213198
RefSeq Peptide - NP_998363
swissprot - Q6P0X9
ZFIN ID - ZDB-GENE-040426-2275
Ensembl - ENSDARG00000021579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ORC5ENSGALG00000008175Gallus gallus
 ORC5ENSG00000164815Homo sapiens
 Orc5ENSMUSG00000029012Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020796  Origin recognition complex, subunit 5
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IBA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IBA
 molecular_functionGO:0003688 DNA replication origin binding IBA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000039217 orc1 / origin recognition complex, subunit 1 / Q13415* / Q9Z1N2*  / reaction / complex
 ENSDARG00000008805 orc3 / origin recognition complex, subunit 3 / Q9JK30* / Q9UBD5*  / reaction / complex
 ENSDARG00000075682 orc6 / origin recognition complex, subunit 6 / Q9Y5N6*  / reaction
 ENSDARG00000101161 orc4 / origin recognition complex, subunit 4 / O43929*  / complex / reaction






 

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