ENSDARG00000008805


Danio rerio

Features
Gene ID: ENSDARG00000008805
  
Biological name :orc3
  
Synonyms : orc3 / origin recognition complex, subunit 3
  
Possible biological names infered from orthology : Q9JK30 / Q9UBD5
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 49313504
Gene end: 49339681
  
Corresponding Affymetrix probe sets: Dr.2362.1.S1_at (Zebrafish Array)   NM_212727_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000047856
NCBI entrez gene - 334315     See in Manteia.
RefSeq - NM_212727
RefSeq Peptide - NP_997892
swissprot - F1QP75
ZFIN ID - ZDB-GENE-030131-6247
Ensembl - ENSDARG00000008805
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ORC3ENSGALG00000015800Gallus gallus
 ORC3ENSG00000135336Homo sapiens
 Orc3ENSMUSG00000040044Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020795  Origin recognition complex, subunit 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000039217 orc1 / origin recognition complex, subunit 1 / Q13415* / Q9Z1N2*  / reaction / complex
 ENSDARG00000075682 orc6 / origin recognition complex, subunit 6 / Q9Y5N6*  / reaction
 ENSDARG00000021579 orc5 / origin recognition complex, subunit 5 / O43913* / Q9WUV0*  / reaction / complex
 ENSDARG00000101161 orc4 / origin recognition complex, subunit 4 / O43929*  / reaction / complex






 

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contact: otassy@igbmc.fr