ENSMUSG00000029012


Mus musculus

Features
Gene ID: ENSMUSG00000029012
  
Biological name :Orc5
  
Synonyms : Orc5 / Origin recognition complex subunit 5 / Q9WUV0
  
Possible biological names infered from orthology : O43913
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: A3
Gene start: 22486485
Gene end: 22550429
  
Corresponding Affymetrix probe sets: 10528457 (MoGene1.0st)   1415830_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120214
Ensembl peptide - ENSMUSP00000030872
NCBI entrez gene - 26429     See in Manteia.
MGI - MGI:1347044
RefSeq - NM_011959
RefSeq - XM_006535716
RefSeq Peptide - NP_036089
swissprot - D3Z0X3
swissprot - Q9WUV0
Ensembl - ENSMUSG00000029012
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orc5ENSDARG00000021579Danio rerio
 ORC5ENSGALG00000008175Gallus gallus
 ORC5ENSG00000164815Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020796  Origin recognition complex, subunit 5
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IBA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003688 DNA replication origin binding IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026761 Orc4 / O88708 / Mus musculus origin recognition complex, subunit 4 (Orc4), transcript variant 4, mRNA. / O43929* / origin recognition complex subunit 4*  / reaction / complex
 ENSMUSG00000026037 Orc2 / Q60862 / Origin recognition complex subunit 2 / Q13416*  / complex / reaction
 ENSMUSG00000028587 Orc1 / Q9Z1N2 / Origin recognition complex subunit 1 / Q13415*  / complex / reaction
 ENSMUSG00000040044 Orc3 / Q9JK30 / Origin recognition complex subunit 3 / Q9UBD5*  / reaction / complex






 

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