ENSMUSG00000026037


Mus musculus

Features
Gene ID: ENSMUSG00000026037
  
Biological name :Orc2
  
Synonyms : Orc2 / Origin recognition complex subunit 2 / Q60862
  
Possible biological names infered from orthology : Q13416
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C1.3
Gene start: 58462771
Gene end: 58505109
  
Corresponding Affymetrix probe sets: 10354845 (MoGene1.0st)   1418225_at (Mouse Genome 430 2.0 Array)   1418226_at (Mouse Genome 430 2.0 Array)   1418227_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141138
Ensembl peptide - ENSMUSP00000027198
Ensembl peptide - ENSMUSP00000109964
Ensembl peptide - ENSMUSP00000139869
NCBI entrez gene - 18393     See in Manteia.
MGI - MGI:1328306
RefSeq - XM_011238453
RefSeq - NM_001025378
RefSeq - NM_001271526
RefSeq - NM_008765
RefSeq Peptide - NP_001258455
RefSeq Peptide - NP_032791
RefSeq Peptide - NP_001020549
swissprot - Q59IX1
swissprot - A0A087WPP9
swissprot - Q60862
swissprot - Q543F8
swissprot - A0A087WSP9
Ensembl - ENSMUSG00000026037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 orc2ENSDARG00000101465Danio rerio
 ORC2ENSGALG00000008234Gallus gallus
 ORC2ENSG00000115942Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007220  Origin recognition complex, subunit 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 cellular_componentGO:0000784 nuclear chromosome, telomeric region IEA
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0000808 origin recognition complex IEA
 cellular_componentGO:0000939 condensed chromosome inner kinetochore IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005664 nuclear origin of replication recognition complex IEA
 cellular_componentGO:0005813 centrosome IEA
 molecular_functionGO:0003688 DNA replication origin binding IDA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026761 Orc4 / O88708 / Mus musculus origin recognition complex, subunit 4 (Orc4), transcript variant 4, mRNA. / O43929* / origin recognition complex subunit 4*  / complex / reaction
 ENSMUSG00000029012 Orc5 / Q9WUV0 / Origin recognition complex subunit 5 / O43913*  / complex / reaction
 ENSMUSG00000028587 Orc1 / Q9Z1N2 / Origin recognition complex subunit 1 / Q13415*  / complex / reaction
 ENSMUSG00000027353 Mcm8 / Q9CWV1 / DNA helicase MCM8 / Q9UJA3* / minichromosome maintenance 8 homologous recombination repair factor*  / complex
 ENSMUSG00000040044 Orc3 / Q9JK30 / Origin recognition complex subunit 3 / Q9UBD5*  / complex / reaction






 

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