ENSMUSG00000031818


Mus musculus

Features
Gene ID: ENSMUSG00000031818
  
Biological name :Cox4i1
  
Synonyms : Cox4i1 / Cytochrome c oxidase subunit 4 isoform 1, mitochondrial / P19783
  
Possible biological names infered from orthology : cytochrome c oxidase subunit 4I1 / P13073
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 120668222
Gene end: 120674207
  
Corresponding Affymetrix probe sets: 10576029 (MoGene1.0st)   1448322_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034276
Ensembl peptide - ENSMUSP00000138019
Ensembl peptide - ENSMUSP00000138053
Ensembl peptide - ENSMUSP00000138063
NCBI entrez gene - 12857     See in Manteia.
MGI - MGI:88473
RefSeq - NM_001293559
RefSeq - NM_009941
RefSeq Peptide - NP_001280488
RefSeq Peptide - NP_034071
swissprot - P19783
swissprot - A2RSV8
swissprot - M0QWX2
swissprot - M0QWX7
Ensembl - ENSMUSG00000031818
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cox4i1ENSDARG00000032970Danio rerio
 COX4I1ENSGALG00000005749Gallus gallus
 COX4I1ENSG00000131143Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cox4i2 / Q91W29 / Cytochrome c oxidase subunit 4 isoform 2, mitochondrial / Q96KJ9* / cytochrome c oxidase subunit 4I2*ENSMUSG0000000987646


Protein motifs (from Interpro)
Interpro ID Name
 IPR004203  Cytochrome c oxidase subunit IV family
 IPR013288  Cytochrome c oxidase subunit IV
 IPR036639  Cytochrome c oxidase subunit IV superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006123 mitochondrial electron transport, cytochrome c to oxygen IBA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:1902600 proton transmembrane transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005751 mitochondrial respiratory chain complex IV ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IDA
 molecular_functionGO:0004129 cytochrome-c oxidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0001697 abnormal embryo size "anomalous proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0003720 abnormal neural tube closure "abnormal invagination and fusion of the neuroepithelial layer in early development" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:99099]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0003864 abnormal midbrain development "anomaly in the formation of or the patterning of the part of the brainstem developing from the middle of the three primary cerebral vesicles of the embryo" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0006108 abnormal hindbrain development "anomaly in the formation or pattering of the caudal region of the brain" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93573]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0009931 abnormal skin appearance "skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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