ENSMUSG00000031922


Mus musculus

Features
Gene ID: ENSMUSG00000031922
  
Biological name :Cep57
  
Synonyms : Centrosomal protein of 57 kDa / Cep57 / Q8CEE0
  
Possible biological names infered from orthology : centrosomal protein 57 / Q86XR8
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A1
Gene start: 13807792
Gene end: 13827107
  
Corresponding Affymetrix probe sets: 10590892 (MoGene1.0st)   1428968_at (Mouse Genome 430 2.0 Array)   1452983_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114940
Ensembl peptide - ENSMUSP00000119081
Ensembl peptide - ENSMUSP00000116931
Ensembl peptide - ENSMUSP00000116847
Ensembl peptide - ENSMUSP00000116713
Ensembl peptide - ENSMUSP00000115338
Ensembl peptide - ENSMUSP00000034398
Ensembl peptide - ENSMUSP00000114665
Ensembl peptide - ENSMUSP00000114749
NCBI entrez gene - 74360     See in Manteia.
MGI - MGI:1915551
RefSeq - XM_017313667
RefSeq - NM_001310721
RefSeq - NM_026665
RefSeq - XM_006510649
RefSeq - XM_006510650
RefSeq Peptide - NP_001297650
RefSeq Peptide - NP_080941
swissprot - D6RH89
swissprot - D6RDE1
swissprot - B8JJF0
swissprot - B8JJE7
swissprot - D6RDR1
swissprot - F7BGJ9
swissprot - Q8CEE0
Ensembl - ENSMUSG00000031922
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep57ENSDARG00000067668Danio rerio
 CEP57ENSGALG00000017201Gallus gallus
 CEP57ENSG00000166037Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cep57l1 / centrosomal protein CEP57L1 isoform 3 / Q8IYX8* / centrosomal protein 57 like 1*ENSMUSG0000001981326


Protein motifs (from Interpro)
Interpro ID Name
 IPR010597  Centrosomal protein 57kDa
 IPR024957  Cep57 centrosome microtubule-binding domain
 IPR025913  Cep57 centrosome localisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IMP
 biological_processGO:0000070 mitotic sister chromatid segregation IBA
 biological_processGO:0007286 spermatid development IEP
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway ISO
 biological_processGO:0034453 microtubule anchoring IEA
 biological_processGO:0051260 protein homooligomerization IPI
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0017134 fibroblast growth factor binding ISS
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0043015 gamma-tubulin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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