ENSMUSG00000032425


Mus musculus

Features
Gene ID: ENSMUSG00000032425
  
Biological name :Zfp949
  
Synonyms : Zfp949 / zinc finger protein 949
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: E3.1
Gene start: 88548020
Gene end: 88571061
  
Corresponding Affymetrix probe sets: 10587655 (MoGene1.0st)   1456518_at (Mouse Genome 430 2.0 Array)   1458491_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125222
Ensembl peptide - ENSMUSP00000125325
Ensembl peptide - ENSMUSP00000124521
Ensembl peptide - ENSMUSP00000125017
NCBI entrez gene - 71640     See in Manteia.
MGI - MGI:1918890
RefSeq - XM_017313597
RefSeq - XM_006511446
RefSeq - NM_001142943
RefSeq - NM_001163061
RefSeq - XM_017313596
RefSeq Peptide - NP_001136415
RefSeq Peptide - NP_001156533
swissprot - E9Q732
swissprot - E0CY31
Ensembl - ENSMUSG00000032425
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfp39 / Q02525 / zinc finger protein 39 / ZNF717* / zinc finger protein 717*ENSMUSG0000003700143
Zfp157 / zinc finger protein 157 / ZNF717* / zinc finger protein 717*ENSMUSG0000003689842
2610008E11Rik / RIKEN cDNA 2610008E11 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000006030141
Zfp68 / zinc finger protein 68 / ZNF717* / zinc finger protein 717*ENSMUSG0000005829139
Zfp599 / zinc finger protein 599 / ZNF717* / zinc finger protein 717*ENSMUSG0000006279439
Zfp810 / zinc finger protein 810 / ZNF717* / zinc finger protein 717*ENSMUSG0000006682938
A430033K04Rik / RIKEN cDNA A430033K04 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000005601438
Gm12258 / ZNF717* / zinc finger protein 717*ENSMUSG0000007291538
2810021J22Rik / RIKEN cDNA 2810021J22 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000002049133
G3X9G7 / Zfp809 / zinc finger protein 809 / ZNF717* / zinc finger protein 717*ENSMUSG0000005798227


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

Allelic Composition: Cdkn1btm1Kin/Cdkn1btm1Kin,Zfp949tm1Htno/Zfp949tm1Htno
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

Allelic Composition: Cdkn1btm1Kin/Cdkn1btm1Kin,Zfp949tm1Htno/Zfp949tm1Htno
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0001700 abnormal embryo turning "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdkn1btm1Kin/Cdkn1btm1Kin,Zfp949tm1Htno/Zfp949tm1Htno
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0004180 failure of initiation of embryo turning "failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0005657 abnormal neural plate morphology "malformation or absence of the neuroectodermal area of the embryo s dorsal surface that develops into the neural tube and neural crest" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator, J:68142]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

Allelic Composition: Cdkn1btm1Kin/Cdkn1btm1Kin,Zfp949tm1Htno/Zfp949tm1Htno
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0011107 partial embryonic lethality before turning of embryo "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Golgb1em8Lanyu/Golgb1em33Lanyu
Genetic Background: FVB/NJ-Golgb1em8Lanyu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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