ENSMUSG00000036898


Mus musculus

Features
Gene ID: ENSMUSG00000036898
  
Biological name :Zfp157
  
Synonyms : Zfp157 / zinc finger protein 157
  
Possible biological names infered from orthology : zinc finger protein 717 / ZNF717
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: G2
Gene start: 138441468
Gene end: 138460694
  
Corresponding Affymetrix probe sets: 10526842 (MoGene1.0st)   1428887_at (Mouse Genome 430 2.0 Array)   1452945_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098093
Ensembl peptide - ENSMUSP00000106537
Ensembl peptide - ENSMUSP00000083018
NCBI entrez gene - 72154     See in Manteia.
MGI - MGI:1919404
RefSeq - XM_006504625
RefSeq - XM_006504627
RefSeq - NM_028130
RefSeq Peptide - NP_082406
swissprot - Q6PCM4
swissprot - D3Z0U7
swissprot - D3YYT4
Ensembl - ENSMUSG00000036898
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ZNF717ENSG00000227124Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
2610008E11Rik / RIKEN cDNA 2610008E11 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000006030150
Zfp810 / zinc finger protein 810 / ZNF717* / zinc finger protein 717*ENSMUSG0000006682949
Zfp39 / Q02525 / zinc finger protein 39 / ZNF717* / zinc finger protein 717*ENSMUSG0000003700145
Zfp599 / zinc finger protein 599 / ZNF717* / zinc finger protein 717*ENSMUSG0000006279445
Zfp949 / zinc finger protein 949ENSMUSG0000003242545
A430033K04Rik / RIKEN cDNA A430033K04 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000005601442
Zfp68 / zinc finger protein 68 / ZNF717* / zinc finger protein 717*ENSMUSG0000005829142
Gm12258 / ZNF717* / zinc finger protein 717*ENSMUSG0000007291537
2810021J22Rik / RIKEN cDNA 2810021J22 gene / ZNF717* / zinc finger protein 717*ENSMUSG0000002049133
G3X9G7 / Zfp809 / zinc finger protein 809 / ZNF717* / zinc finger protein 717*ENSMUSG0000005798232


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010453 regulation of cell fate commitment IMP
 biological_processGO:0048286 lung alveolus development IMP
 biological_processGO:0060443 mammary gland morphogenesis IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000627 abnormal mammary gland morphology "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183]
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0000628 abnormal mammary gland development "aberration in the differentiation of the mammary gland during early embryogenesis or during sexual maturity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001881 abnormal mammary gland physiology "aberrant function of of the milk-secreting gland that lies within the breast" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001884 mammary alveolar hyperplasia 
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0006269 abnormal mammary gland growth during pregnancy "anomaly in the extensive and rapid branching of the mammary ducts, expansion of mammary epithelium in the stroma between the ducts with or without abnormalities in nipple maturation " [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0013781 abnormal mammary gland luminal epithelium morphology "any structural anomaly of the inner cell layer of the mammary epithelium bilayer that lines the luminal surface of mammary gland ducts and alveoli; luminal cells have only limited contact with the underlying basement membrane and surrounding connective tissue; they are secretory epithelial cells characterized by the expression of the receptors for systemic hormones, i.e. estrogens, progesterone and prolactin" [http://umr144.curie.fr/en/research-groups/molecular-mechanisms-mammary-gland-development-marina-glukhova/molecular-mechanisms-, ISBN:8793237073, MGI:Anna]
Show

Allelic Composition: Pak2tm1Dgen/Pak2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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