ENSMUSG00000032565


Mus musculus

Features
Gene ID: ENSMUSG00000032565
  
Biological name :Nudt16
  
Synonyms : Nudt16 / Q6P3D0 / U8 snoRNA-decapping enzyme
  
Possible biological names infered from orthology : nudix hydrolase 16 / Q96DE0
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: F1
Gene start: 105128903
Gene end: 105131824
  
Corresponding Affymetrix probe sets: 10596318 (MoGene1.0st)   1421204_a_at (Mouse Genome 430 2.0 Array)   1439884_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035179
Ensembl peptide - ENSMUSP00000140976
Ensembl peptide - ENSMUSP00000140590
NCBI entrez gene - 75686     See in Manteia.
MGI - MGI:1922936
RefSeq - NM_029385
RefSeq - XM_006511845
RefSeq Peptide - NP_083661
swissprot - A0A087WSB5
swissprot - Q6P3D0
swissprot - A0A087WRE5
Ensembl - ENSMUSG00000032565
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:103759ENSDARG00000019503Danio rerio
 NUDT16ENSG00000198585Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
1700080E11Rik / RIKEN cDNA 1700080E11 gene / NUDT16* / Q96DE0* / nudix hydrolase 16*ENSMUSG0000003256667
Q8VHN8 / Nudt16l1 / Tudor-interacting repair regulator protein / Q9BRJ7* / nudix hydrolase 16 like 1*ENSMUSG0000002251652


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006382 adenosine to inosine editing ISO
 biological_processGO:0006402 mRNA catabolic process IMP
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0009117 nucleotide metabolic process IEA
 biological_processGO:0016077 snoRNA catabolic process ISO
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035863 dITP catabolic process IGI
 biological_processGO:0046709 IDP catabolic process ISO
 biological_processGO:0051276 chromosome organization IGI
 biological_processGO:0090068 positive regulation of cell cycle process ISS
 biological_processGO:1901639 XDP catabolic process ISO
 biological_processGO:2000233 negative regulation of rRNA processing ISS
 biological_processGO:2000781 positive regulation of double-strand break repair ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding ISS
 molecular_functionGO:0005525 GTP binding ISO
 molecular_functionGO:0008235 metalloexopeptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding ISO
 molecular_functionGO:0030515 snoRNA binding ISO
 molecular_functionGO:0035870 dITP diphosphatase activity IMP
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050072 m7G(5")pppN diphosphatase activity ISO
 molecular_functionGO:0050897 cobalt ion binding ISS
 molecular_functionGO:0097383 dIDP diphosphatase activity ISO
 molecular_functionGO:0098519 nucleotide phosphatase activity, acting on free nucleotides ISO
 molecular_functionGO:1901640 XTP binding ISO
 molecular_functionGO:1901641 ITP binding ISO
 molecular_functionGO:1990003 IDP phosphatase activity ISO


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NUDT proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032565 Nudt16 / Q6P3D0 / U8 snoRNA-decapping enzyme / Q96DE0* / nudix hydrolase 16*  / complex
 ENSMUSG00000032566 1700080E11Rik / RIKEN cDNA 1700080E11 gene / NUDT16* / Q96DE0* / nudix hydrolase 16*  / complex






 

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