ENSMUSG00000032586


Mus musculus

Features
Gene ID: ENSMUSG00000032586
  
Biological name :Traip
  
Synonyms : E3 ubiquitin-protein ligase TRAIP / Q8VIG6 / Traip
  
Possible biological names infered from orthology : Q9BWF2 / TRAF interacting protein
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F1
Gene start: 107950136
Gene end: 107972270
  
Corresponding Affymetrix probe sets: 10588767 (MoGene1.0st)   1420707_a_at (Mouse Genome 430 2.0 Array)   1420708_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040001
Ensembl peptide - ENSMUSP00000141689
NCBI entrez gene - 22036     See in Manteia.
MGI - MGI:1096377
RefSeq - XM_017313284
RefSeq - NM_011634
RefSeq - XM_006511693
RefSeq - XM_006511694
RefSeq Peptide - NP_035764
swissprot - A0A0A6YWT5
swissprot - Q8VIG6
Ensembl - ENSMUSG00000032586
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 traipENSDARG00000011262Danio rerio
 TRAIPENSGALG00000002908Gallus gallus
 TRAIPENSG00000183763Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IPI
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0032688 negative regulation of interferon-beta production IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0011198 absent proamniotic cavity "absence of the cavity of the developing embryo that is formed within the epiblast tissue prior to the closing of the proamniotic canal by the amniotic folds" [ISBN:0-12-402035-6]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0013504 increased embryonic tissue cell apoptosis "increase in the timing or the number of cells in embryonic tissue undergoing programmed cell death" [MGI:csmith]
Show

Allelic Composition: Ctsktm1(cre)Ska/Ctsk+,Esr1tm1Mma/Esr1tm1Mma
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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