ENSMUSG00000032598


Mus musculus

Features
Gene ID: ENSMUSG00000032598
  
Biological name :Nckipsd
  
Synonyms : NCK-interacting protein with SH3 domain / Nckipsd / Q9ESJ4
  
Possible biological names infered from orthology : Q9NZQ3
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F2
Gene start: 108808368
Gene end: 108818844
  
Corresponding Affymetrix probe sets: 10589113 (MoGene1.0st)   1418975_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035218
Ensembl peptide - ENSMUSP00000141857
Ensembl peptide - ENSMUSP00000141728
Ensembl peptide - ENSMUSP00000141702
NCBI entrez gene - 80987     See in Manteia.
MGI - MGI:1931834
RefSeq - XM_006511860
RefSeq - NM_030729
RefSeq Peptide - NP_109654
swissprot - A0A0A6YWW3
swissprot - A0A0A6YX64
swissprot - Q9ESJ4
swissprot - A0A0A6YWU4
Ensembl - ENSMUSG00000032598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nckipsdENSDARG00000079475Danio rerio
 NCKIPSDENSGALG00000005713Gallus gallus
 Q9NZQ3ENSG00000213672Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR011989  Armadillo-like helical
 IPR018556  Domain of unknown function DUF2013
 IPR035514  SPIN90, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010976 positive regulation of neuron projection development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Eif3cXs-J/Eif3c+
Genetic Background: B6C3Fe a/a-Eif3cXs-J/J

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Rettm2.1Cos/Rettm2.1Cos
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0003091 abnormal cell migration "defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Eif3cXs-J/Eif3c+
Genetic Background: B6C3Fe a/a-Eif3cXs-J/J

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Eif3cXs-J/Eif3c+
Genetic Background: B6C3Fe a/a-Eif3cXs-J/J

 MP:0020378 abnormal cell cytoskeleton morphology "any anomaly in the structure of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm" [GO:0005856, MGI:mberry]
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Allelic Composition: Rettm2.1Cos/Rettm2.1Cos
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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