ENSG00000213672


Homo sapiens

Features
Gene ID: ENSG00000213672
  
Biological name :NCKIPSD
  
Synonyms : NCK interacting protein with SH3 domain / NCKIPSD / Q9NZQ3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.31
Gene start: 48673844
Gene end: 48686364
  
Corresponding Affymetrix probe sets: 216114_at (Human Genome U133 Plus 2.0 Array)   216116_at (Human Genome U133 Plus 2.0 Array)   218697_at (Human Genome U133 Plus 2.0 Array)   233165_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408588
Ensembl peptide - ENSP00000406442
Ensembl peptide - ENSP00000409675
Ensembl peptide - ENSP00000416904
Ensembl peptide - ENSP00000416144
Ensembl peptide - ENSP00000294129
Ensembl peptide - ENSP00000389059
Ensembl peptide - ENSP00000396683
NCBI entrez gene - 51517     See in Manteia.
OMIM - 606671
RefSeq - XM_017006600
RefSeq - NM_016453
RefSeq - NM_184231
RefSeq - XM_017006594
RefSeq - XM_017006595
RefSeq - XM_017006596
RefSeq - XM_017006597
RefSeq - XM_017006598
RefSeq - XM_017006599
RefSeq Peptide - NP_909119
RefSeq Peptide - NP_057537
swissprot - C9JMQ4
swissprot - F8WCR8
swissprot - H7C0T9
swissprot - H7C2K2
swissprot - Q9NZQ3
swissprot - C9JC20
swissprot - C9JSC3
Ensembl - ENSG00000213672
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nckipsdENSDARG00000079475Danio rerio
 NCKIPSDENSGALG00000005713Gallus gallus
 Q9ESJ4ENSMUSG00000032598Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR011989  Armadillo-like helical
 IPR018556  Domain of unknown function DUF2013
 IPR035514  SPIN90, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006607 NLS-bearing protein import into nucleus TAS
 biological_processGO:0007010 cytoskeleton organization NAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament NAS
 cellular_componentGO:0008180 COP9 signalosome IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding NAS
 molecular_functionGO:0017124 SH3 domain binding IEA


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000015285 WAS / P42768 / Wiskott-Aldrich syndrome  / reaction
 ENSG00000106299 WASL / O00401 / Wiskott-Aldrich syndrome like  / reaction
 ENSG00000171475 WIPF2 / Q8TF74 / WAS/WASL interacting protein family member 2  / reaction
 ENSG00000115935 WIPF1 / O43516 / WAS/WASL interacting protein family member 1  / reaction
 ENSG00000122574 WIPF3 / A6NGB9 / WAS/WASL interacting protein family member 3  / reaction
 ENSG00000070831 CDC42 / P60953 / cell division cycle 42  / reaction






 

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