ENSG00000171475


Homo sapiens

Features
Gene ID: ENSG00000171475
  
Biological name :WIPF2
  
Synonyms : Q8TF74 / WAS/WASL interacting protein family member 2 / WIPF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.2
Gene start: 40219304
Gene end: 40284136
  
Corresponding Affymetrix probe sets: 212049_at (Human Genome U133 Plus 2.0 Array)   212050_at (Human Genome U133 Plus 2.0 Array)   212051_at (Human Genome U133 Plus 2.0 Array)   231251_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463149
Ensembl peptide - ENSP00000462826
Ensembl peptide - ENSP00000463869
Ensembl peptide - ENSP00000320924
Ensembl peptide - ENSP00000377663
Ensembl peptide - ENSP00000462350
Ensembl peptide - ENSP00000462386
NCBI entrez gene - 147179     See in Manteia.
OMIM - 609692
RefSeq - XM_011524413
RefSeq - NM_133264
RefSeq - XM_005257083
RefSeq - XM_005257084
RefSeq - XM_011524412
RefSeq Peptide - NP_573571
swissprot - Q8TF74
swissprot - J3KSA3
swissprot - J3QKM5
swissprot - J3QQS0
swissprot - A8MWR2
Ensembl - ENSG00000171475
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wipf2aENSDARG00000045298Danio rerio
 wipf2bENSDARG00000006712Danio rerio
 WIPF2ENSGALG00000037633Gallus gallus
 Wipf2ENSMUSG00000038013Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WIPF3 / A6NGB9 / WAS/WASL interacting protein family member 3ENSG0000012257436


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR028294  WAS/WASL-interacting protein family member 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of actin dynamics for phagocytic cup formation
RHO GTPases Activate WASPs and WAVEs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000158092 NCK1 / P16333 / NCK adaptor protein 1  / reaction
 ENSG00000213672 Q9NZQ3 / NCKIPSD / NCK interacting protein with SH3 domain  / reaction
 ENSG00000177885 GRB2 / P62993 / growth factor receptor bound protein 2  / reaction
 ENSG00000015285 WAS / P42768 / Wiskott-Aldrich syndrome  / reaction
 ENSG00000070831 CDC42 / P60953 / cell division cycle 42  / reaction
 ENSG00000106299 WASL / O00401 / Wiskott-Aldrich syndrome like  / reaction






 

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