ENSMUSG00000033486


Mus musculus

Features
Gene ID: ENSMUSG00000033486
  
Biological name :Catsper2
  
Synonyms : Catsper2
  
Possible biological names infered from orthology : AC011330.3 / cation channel sperm associated 2 / Q96P56
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 121392631
Gene end: 121413792
  
Corresponding Affymetrix probe sets: 10486819 (MoGene1.0st)   1425309_at (Mouse Genome 430 2.0 Array)   1445264_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119091
Ensembl peptide - ENSMUSP00000037222
NCBI entrez gene - 212670     See in Manteia.
MGI - MGI:2387404
RefSeq - XM_017316898
RefSeq - XM_011239413
RefSeq - XM_011239414
RefSeq - XM_017316895
RefSeq - NM_153075
RefSeq - XM_006499080
RefSeq - XM_006499081
RefSeq - XM_006499082
RefSeq - XM_006499083
RefSeq - XM_006499084
RefSeq Peptide - NP_694715
swissprot - D6RCY8
swissprot - A0A0A0MQ85
Ensembl - ENSMUSG00000033486
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC011330.3ENSG00000284772Homo sapiens
 Q96P56ENSG00000166762Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005821  Ion transport domain
 IPR028747  Cation channel sperm-associated protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0030317 flagellated sperm motility IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0036128 CatSper complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005227 calcium activated cation channel activity IEA


Pathways (from Reactome)
Pathway description
Sperm Motility And Taxes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Blmtm1Ches/Blmtm3Brd
Genetic Background: involves: 129S/SvEv * C57BL/6 * NIH Black Swiss

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Blmtm1Ches/Blmtm3Brd
Genetic Background: involves: 129S/SvEv * C57BL/6 * NIH Black Swiss

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pdgfratm6Sor/Pdgfratm6Sor
Genetic Background: either: 129S4/SvJaeSor-Pdgfratm6Sor or (involves: 129S4/SvJaeSor * C57BL/6J)

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Blmtm1Ches/Blmtm3Brd
Genetic Background: involves: 129S/SvEv * C57BL/6 * NIH Black Swiss

Allelic Composition: Catsper2tm1Gar/Catsper2tm1Gar
Genetic Background: involves: 129S6/SvEvTac

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Blmtm1Ches/Blmtm3Brd
Genetic Background: involves: 129S/SvEv * C57BL/6 * NIH Black Swiss

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Catsper2tm1Gar/Catsper2tm1Gar
Genetic Background: involves: 129S6/SvEvTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000038498 Q91ZR5 / Catsper1 / Cation channel sperm-associated protein 1 / Q8NEC5* / cation channel sperm associated 1*  / complex
 ENSMUSG00000048003 Q8BVN3 / Catsper4 / Cation channel sperm-associated protein 4 / Q7RTX7* / cation channel sperm associated 4*  / complex
 ENSMUSG00000033486 Catsper2 / Q96P56* / AC011330.3* / cation channel sperm associated 2*  / complex
 ENSMUSG00000021499 Q80W99 / Catsper3 / Cation channel sperm-associated protein 3 / Q86XQ3* / cation channel sperm associated 3*  / complex
 ENSMUSG00000049676 E9Q355 / Catsperg1 / Cation channel sperm-associated protein subunit gamma 1 / Q6ZRH7* / CATSPERG* / cation channel sperm associated auxiliary subunit gamma*  / complex
 ENSMUSG00000047014 A2RTF1 / Catsperb / Cation channel sperm-associated protein subunit beta / Q9H7T0* / cation channel sperm associated auxiliary subunit beta*  / complex
 ENSMUSG00000049123 C6KI89 / Catsperg2 / Cation channel sperm-associated protein subunit gamma 2 / Q6ZRH7* / CATSPERG* / cation channel sperm associated auxiliary subunit gamma*  / complex
 ENSMUSG00000040828 E9Q9F6 / Catsperd / Cation channel sperm-associated protein subunit delta / Q86XM0* / cation channel sperm associated auxiliary subunit delta*  / complex






 

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