ENSMUSG00000033557


Mus musculus

Features
Gene ID: ENSMUSG00000033557
  
Biological name :Fam20b
  
Synonyms : Fam20b / Glycosaminoglycan xylosylkinase / Q8VCS3
  
Possible biological names infered from orthology : FAM20B, glycosaminoglycan xylosylkinase / O75063
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: G3
Gene start: 156678532
Gene end: 156719086
  
Corresponding Affymetrix probe sets: 10359190 (MoGene1.0st)   1451667_at (Mouse Genome 430 2.0 Array)   1451668_at (Mouse Genome 430 2.0 Array)   1458111_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000083322
Ensembl peptide - ENSMUSP00000112534
NCBI entrez gene - 215015     See in Manteia.
MGI - MGI:2443990
RefSeq - XM_006496737
RefSeq - NM_145413
RefSeq - XM_006496736
RefSeq Peptide - NP_663388
swissprot - Q8VCS3
Ensembl - ENSMUSG00000033557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fam20bENSDARG00000008573Danio rerio
 FAM20BENSGALG00000004227Gallus gallus
 FAM20BENSG00000116199Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fam20a / Q8CID3 / Pseudokinase FAM20A / Q96MK3* / FAM20A, golgi associated secretory pathway pseudokinase*ENSMUSG0000002061438
Fam20c / Q5MJS3 / Extracellular serine/threonine protein kinase FAM20C / Q8IXL6* / FAM20C, golgi associated secretory pathway kinase*ENSMUSG0000002585437


Protein motifs (from Interpro)
Interpro ID Name
 IPR009581  FAM20, C-terminal
 IPR024869  FAM20


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016773 phosphotransferase activity, alcohol group as acceptor ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000597 delayed hepatic development "late onset of the induction and/or differentiation of the liver" [J:18048]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001286 abnormal eye development "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0003119 abnormal digestive system development "dysmorphology of the organ system that converts ingested food to nutrients and energy" [smb:Susan M. Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Vhltm1Jae/Vhltm1Jae,Tg(NPHS2-cre)295Lbh/?
Genetic Background: involves: 129S4/SvJae * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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