ENSMUSG00000033763


Mus musculus

Features
Gene ID: ENSMUSG00000033763
  
Biological name :Mtss1l
  
Synonyms : Mtss1l / MTSS1-like protein / Q6P9S0
  
Possible biological names infered from orthology : MTSS1L, I-BAR domain containing / Q765P7
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 110721476
Gene end: 110741400
  
Corresponding Affymetrix probe sets: 10575497 (MoGene1.0st)   1435359_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050211
Ensembl peptide - ENSMUSP00000115220
Ensembl peptide - ENSMUSP00000116518
Ensembl peptide - ENSMUSP00000119495
NCBI entrez gene - 244654     See in Manteia.
MGI - MGI:3039591
RefSeq - XM_006531018
RefSeq - XM_006531012
RefSeq - XM_006531013
RefSeq - XM_006531014
RefSeq - XM_006531015
RefSeq - XM_006531016
RefSeq - XM_006531017
RefSeq - NM_001310591
RefSeq - NM_198625
RefSeq - XM_006531011
RefSeq Peptide - NP_001297520
RefSeq Peptide - NP_941027
swissprot - F7D291
swissprot - F6S054
swissprot - Q6P9S0
swissprot - D3YWC9
Ensembl - ENSMUSG00000033763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtss1laENSDARG00000028943Danio rerio
 mtss1lbENSDARG00000087260Danio rerio
 MTSS1LENSGALG00000002467Gallus gallus
 MTSS1LENSG00000132613Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mtss1 / metastasis suppressor 1 / O43312* / MTSS1, I-BAR domain containing*ENSMUSG0000002235357


Protein motifs (from Interpro)
Interpro ID Name
 IPR013606  IMD/I-BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR030059  I-BAR domain containing protein ABBA
 IPR030127  I-BAR domain containing protein MIM/ABBA


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007009 plasma membrane organization IEA
 biological_processGO:0036120 cellular response to platelet-derived growth factor stimulus IEA
 biological_processGO:0061024 membrane organization IDA
 biological_processGO:0090630 activation of GTPase activity IEA
 biological_processGO:0097178 ruffle assembly IEA
 biological_processGO:0097581 lamellipodium organization IMP
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030864 cortical actin cytoskeleton IDA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0048365 Rac GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001566 hyperphosphatemia "abnormally high concentrations of phosphates in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Msx1tm1b(KOMP)Wtsi/Msx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Msx1tm1b(KOMP)Wtsi/J

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Msx1tm1b(KOMP)Wtsi/Msx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Msx1tm1b(KOMP)Wtsi/J

 MP:0003020 decreased circulating chloride level "reduced concentration of chlorine salts in the circulation" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Msx1tm1b(KOMP)Wtsi/Msx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Msx1tm1b(KOMP)Wtsi/J

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Msx1tm1b(KOMP)Wtsi/Msx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Msx1tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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