ENSMUSG00000033902


Mus musculus

Features
Gene ID: ENSMUSG00000033902
  
Biological name :Mapkbp1
  
Synonyms : Mapkbp1 / Mus musculus mitogen-activated protein kinase binding protein 1 (Mapkbp1), transcript variant 1, mRNA.
  
Possible biological names infered from orthology : mitogen-activated protein kinase binding protein 1 / O60336
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: E5
Gene start: 119972699
Gene end: 120027408
  
Corresponding Affymetrix probe sets: 10475080 (MoGene1.0st)   1423403_at (Mouse Genome 430 2.0 Array)   1450973_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000068516
Ensembl peptide - ENSMUSP00000155163
NCBI entrez gene - 26390     See in Manteia.
MGI - MGI:1347004
RefSeq - XM_017318653
RefSeq - NM_001355293
RefSeq - NM_011941
RefSeq - XM_006499587
RefSeq - XM_006499588
RefSeq - XM_006499589
RefSeq Peptide - NP_001342222
RefSeq Peptide - NP_036071
swissprot - A0A0A0MQA2
Ensembl - ENSMUSG00000033902
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mapkbp1ENSDARG00000103746Danio rerio
 ENSGALG00000008692Gallus gallus
 O60336ENSG00000137802Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wdr62 / WD repeat domain 62 / O43379*ENSMUSG0000003702038


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:1900425 negative regulation of defense response to bacterium IEA
 biological_processGO:2000483 negative regulation of interleukin-8 secretion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0097431 mitotic spindle pole IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0003382 straub tail "condition in which an animal carries its tail in an erect (vertical or nearly vertical) position; often seen upon opioid and other drug treatment" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0003795 abnormal bone structure 
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Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mapkap1tm1b(EUCOMM)Wtsi/Mapkap1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Mapkap1tm1b(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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