ENSMUSG00000034000


Mus musculus

Features
Gene ID: ENSMUSG00000034000
  
Biological name :Neu4
  
Synonyms : Neu4 / Q8BZL1 / Sialidase-4
  
Possible biological names infered from orthology : neuraminidase 4 / Q8WWR8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: D
Gene start: 94020451
Gene end: 94028334
  
Corresponding Affymetrix probe sets: 10348910 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000051151
Ensembl peptide - ENSMUSP00000140127
NCBI entrez gene - 241159     See in Manteia.
MGI - MGI:2661364
RefSeq - NM_001310769
RefSeq - NM_173772
RefSeq Peptide - NP_001297698
RefSeq Peptide - NP_776133
swissprot - Q8BZL1
swissprot - C5NTX9
Ensembl - ENSMUSG00000034000
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neu4ENSDARG00000057677Danio rerio
 NEU4ENSGALG00000006361Gallus gallus
 NEU4ENSG00000204099Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Neu3 / Q9JMH7 / neuraminidase 3 / Q9UQ49*ENSMUSG0000003523938
Neu2 / Q9JMH3 / Sialidase-2 / Q9Y3R4* / neuraminidase 2*ENSMUSG0000007943434


Protein motifs (from Interpro)
Interpro ID Name
 IPR011040  Sialidase
 IPR026856  Sialidase family
 IPR026946  Sialidase-4
 IPR036278  Sialidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006516 glycoprotein catabolic process ISS
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006689 ganglioside catabolic process ISS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process ISO
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0019866 organelle inner membrane ISO
 molecular_functionGO:0004308 exo-alpha-sialidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0052794 exo-alpha-(2->3)-sialidase activity IEA
 molecular_functionGO:0052795 exo-alpha-(2->6)-sialidase activity IEA
 molecular_functionGO:0052796 exo-alpha-(2->8)-sialidase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Pkd1tm1Shh/Pkd1tm1Shh
Genetic Background: involves: 129P2/OlaHsd

 MP:0003172 abnormal lysosome physiology "ability of lysosomes to produce enzymes necessary for digestion of exogenous material is impaired" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pkd1tm1Shh/Pkd1tm1Shh
Genetic Background: involves: 129P2/OlaHsd

 MP:0003982 increased cholesterol level "greater than normal concentration in the body of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Pkd1tm1Shh/Pkd1tm1Shh
Genetic Background: involves: 129P2/OlaHsd

 MP:0005283 increased unsaturated fatty acid level "greater than normal non-circulating level of organic, monobasic acids derived from hydrocarbons in which the carbon chain has one or more double or triple carbon-carbon bonds " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pkd1tm1Shh/Pkd1tm1Shh
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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