ENSG00000204099


Homo sapiens

Features
Gene ID: ENSG00000204099
  
Biological name :NEU4
  
Synonyms : NEU4 / neuraminidase 4 / Q8WWR8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.3
Gene start: 241808825
Gene end: 241817413
  
Corresponding Affymetrix probe sets: 222957_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385149
Ensembl peptide - ENSP00000412688
Ensembl peptide - ENSP00000406678
Ensembl peptide - ENSP00000398571
Ensembl peptide - ENSP00000397860
Ensembl peptide - ENSP00000397167
Ensembl peptide - ENSP00000396197
Ensembl peptide - ENSP00000394769
Ensembl peptide - ENSP00000388707
Ensembl peptide - ENSP00000385402
Ensembl peptide - ENSP00000320318
Ensembl peptide - ENSP00000375830
Ensembl peptide - ENSP00000384804
NCBI entrez gene - 129807     See in Manteia.
OMIM - 608527
RefSeq - NM_001167601
RefSeq - NM_001167602
RefSeq - NM_080741
RefSeq - NM_001167600
RefSeq - NM_001167599
RefSeq Peptide - NP_001161073
RefSeq Peptide - NP_001161074
RefSeq Peptide - NP_542779
RefSeq Peptide - NP_001161071
RefSeq Peptide - NP_001161072
swissprot - Q8WWR8
swissprot - C9JEA3
swissprot - C9J5X2
swissprot - C9J2V4
swissprot - C9J2R4
swissprot - C9J295
swissprot - C9IZG9
swissprot - B3KR54
swissprot - F8WE58
swissprot - C9JRN9
Ensembl - ENSG00000204099
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neu4ENSDARG00000057677Danio rerio
 NEU4ENSGALG00000006361Gallus gallus
 Neu4ENSMUSG00000034000Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEU3 / Q9UQ49 / neuraminidase 3ENSG0000016213937
NEU2 / Q9Y3R4 / neuraminidase 2ENSG0000011548834


Protein motifs (from Interpro)
Interpro ID Name
 IPR011040  Sialidase
 IPR026856  Sialidase family
 IPR026946  Sialidase-4
 IPR036278  Sialidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006516 glycoprotein catabolic process IDA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0006689 ganglioside catabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process IDA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019866 organelle inner membrane IDA
 cellular_componentGO:0043202 lysosomal lumen TAS
 molecular_functionGO:0004308 exo-alpha-sialidase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0052794 exo-alpha-(2->3)-sialidase activity IEA
 molecular_functionGO:0052795 exo-alpha-(2->6)-sialidase activity IEA
 molecular_functionGO:0052796 exo-alpha-(2->8)-sialidase activity IEA


Pathways (from Reactome)
Pathway description
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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