ENSG00000115488


Homo sapiens

Features
Gene ID: ENSG00000115488
  
Biological name :NEU2
  
Synonyms : NEU2 / neuraminidase 2 / Q9Y3R4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 233032672
Gene end: 233035057
  
Corresponding Affymetrix probe sets: 221368_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000233840
NCBI entrez gene - 4759     See in Manteia.
OMIM - 605528
RefSeq - NM_005383
RefSeq Peptide - NP_005374
swissprot - Q9Y3R4
Ensembl - ENSG00000115488
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Neu2ENSMUSG00000079434Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEU4 / Q8WWR8 / neuraminidase 4ENSG0000020409944
NEU3 / Q9UQ49 / neuraminidase 3ENSG0000016213942


Protein motifs (from Interpro)
Interpro ID Name
 IPR011040  Sialidase
 IPR026856  Sialidase family
 IPR026945  Sialidase-2
 IPR036278  Sialidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0006689 ganglioside catabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process IDA
 biological_processGO:0016042 lipid catabolic process IEA
 biological_processGO:0051692 cellular oligosaccharide catabolic process IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 cellular_componentGO:1902494 catalytic complex IDA
 molecular_functionGO:0004308 exo-alpha-sialidase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0052794 exo-alpha-(2->3)-sialidase activity IEA
 molecular_functionGO:0052795 exo-alpha-(2->6)-sialidase activity IEA
 molecular_functionGO:0052796 exo-alpha-(2->8)-sialidase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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