ENSG00000162139


Homo sapiens

Features
Gene ID: ENSG00000162139
  
Biological name :NEU3
  
Synonyms : NEU3 / neuraminidase 3 / Q9UQ49
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 74988134
Gene end: 75018893
  
Corresponding Affymetrix probe sets: 206948_at (Human Genome U133 Plus 2.0 Array)   216082_at (Human Genome U133 Plus 2.0 Array)   216083_s_at (Human Genome U133 Plus 2.0 Array)   235474_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294064
Ensembl peptide - ENSP00000436540
Ensembl peptide - ENSP00000436118
Ensembl peptide - ENSP00000434907
Ensembl peptide - ENSP00000434754
Ensembl peptide - ENSP00000434474
Ensembl peptide - ENSP00000432097
NCBI entrez gene - 10825     See in Manteia.
OMIM - 604617
RefSeq - NM_006656
RefSeq Peptide - NP_006647
swissprot - E9PI40
swissprot - A0A024R5N6
swissprot - E9PR25
swissprot - Q9UQ49
swissprot - E9PNK1
swissprot - E9PMZ3
Ensembl - ENSG00000162139
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 neu3.1ENSDARG00000096382Danio rerio
 neu3.2ENSDARG00000010047Danio rerio
 neu3.3ENSDARG00000058327Danio rerio
 neu3.4ENSDARG00000096381Danio rerio
 neu3.5ENSDARG00000096368Danio rerio
 NEU3ENSGALG00000028960Gallus gallus
 Neu3ENSMUSG00000035239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NEU4 / Q8WWR8 / neuraminidase 4ENSG0000020409940
NEU2 / Q9Y3R4 / neuraminidase 2ENSG0000011548834


Protein motifs (from Interpro)
Interpro ID Name
 IPR011040  Sialidase
 IPR026856  Sialidase family
 IPR026944  Sialidase-3
 IPR036278  Sialidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IDA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0006689 ganglioside catabolic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process IDA
 biological_processGO:0016042 lipid catabolic process IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0004308 exo-alpha-sialidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016997 alpha-sialidase activity IDA
 molecular_functionGO:0052794 exo-alpha-(2->3)-sialidase activity ISS
 molecular_functionGO:0052795 exo-alpha-(2->6)-sialidase activity IEA
 molecular_functionGO:0052796 exo-alpha-(2->8)-sialidase activity ISS


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Sialic acid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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