ENSMUSG00000034254


Mus musculus

Features
Gene ID: ENSMUSG00000034254
  
Biological name :Agpat1
  
Synonyms : 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) / Agpat1
  
Possible biological names infered from orthology : 1-acylglycerol-3-phosphate O-acyltransferase 1 / Q99943
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 34604262
Gene end: 34613449
  
Corresponding Affymetrix probe sets: 10444420 (MoGene1.0st)   1421024_at (Mouse Genome 430 2.0 Array)   1421025_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134358
Ensembl peptide - ENSMUSP00000133947
Ensembl peptide - ENSMUSP00000134242
Ensembl peptide - ENSMUSP00000048573
Ensembl peptide - ENSMUSP00000109776
Ensembl peptide - ENSMUSP00000133441
Ensembl peptide - ENSMUSP00000133876
NCBI entrez gene - 55979     See in Manteia.
MGI - MGI:1932075
RefSeq - XM_006524648
RefSeq - NM_001163379
RefSeq - NM_018862
RefSeq - XM_006524647
RefSeq Peptide - NP_001156851
RefSeq Peptide - NP_061350
swissprot - A0A0R4J263
swissprot - G3UWV6
swissprot - G3UXY8
swissprot - G3UY51
swissprot - G3UYV9
Ensembl - ENSMUSG00000034254
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000045455Gallus gallus
 ENSGALG00000044527Gallus gallus
 AGPAT1ENSG00000204310Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Agpat2 / Q8K3K7 / 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) / O15120* / 1-acylglycerol-3-phosphate O-acyltransferase 2*ENSMUSG0000002692243


Protein motifs (from Interpro)
Interpro ID Name
 IPR002123  Phospholipid/glycerol acyltransferase
 IPR004552  1-acyl-sn-glycerol-3-phosphate acyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008654 phospholipid biosynthetic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA
ChREBP activates metabolic gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000195 hypocalcemia "subnormal concentrations of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0003928 increased heart rate variability "increased variation of beat-to-beat intervals of the heart, usually indicitive of a healthy heart" [RGD:Rat Genome Database submission]
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Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0005641 increased mean corpuscular hemoglobin concentration "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Adipor1tm1b(EUCOMM)Hmgu/Adipor1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Adipor1tm1b(EUCOMM)Hmgu/H

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: 4932438A13Riktm1b(EUCOMM)Hmgu/4932438A13Riktm1b(EUCOMM)Hmgu
Genetic Background: B6N(Cg)-4932438A13Riktm1b(EUCOMM)Hmgu/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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