ENSMUSG00000034345


Mus musculus

Features
Gene ID: ENSMUSG00000034345
  
Biological name :Gtf2h5
  
Synonyms : Gtf2h5 / Q8K2X8 / ral transcription factor IIH subunit 5
  
Possible biological names infered from orthology : general transcription factor IIH subunit 5 / Q6ZYL4
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A1
Gene start: 6079786
Gene end: 6086517
  
Corresponding Affymetrix probe sets: 10441489 (MoGene1.0st)   1428906_at (Mouse Genome 430 2.0 Array)   1452955_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040355
Ensembl peptide - ENSMUSP00000098515
NCBI entrez gene - 66467     See in Manteia.
MGI - MGI:107227
RefSeq - XM_006523240
RefSeq - NM_181392
RefSeq - XM_006523239
RefSeq Peptide - NP_001344733
RefSeq Peptide - NP_852057
swissprot - Q8K2X8
Ensembl - ENSMUSG00000034345
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2h5ENSDARG00000056099Danio rerio
 GTF2H5ENSGALG00000013733Gallus gallus
 GTF2H5ENSG00000272047Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009400  TFIIH subunit TTDA/Tfb5
 IPR035935  TFB5-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair ISO
 biological_processGO:0006294 nucleotide-excision repair, preincision complex assembly IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006362 transcription elongation from RNA polymerase I promoter IMP
 biological_processGO:0006364 rRNA processing IMP
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0071480 cellular response to gamma radiation IMP
 cellular_componentGO:0000439 core TFIIH complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005669 transcription factor TFIID complex ISO
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0000182 rDNA binding IDA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Fetubtm1Wja/Fetubtm1Wja
Genetic Background: D2.Cg-Fetubtm1Wja

Allelic Composition: Gtf2h5tm1.1Wive/Gtf2h5tm1.1Wive
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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