ENSMUSG00000034457


Mus musculus

Features
Gene ID: ENSMUSG00000034457
  
Biological name :Eda2r
  
Synonyms : Eda2r / Q8BX35 / Tumor necrosis factor receptor superfamily member 27
  
Possible biological names infered from orthology : ectodysplasin A2 receptor / Q9HAV5
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: C3
Gene start: 97333840
Gene end: 97377216
  
Corresponding Affymetrix probe sets: 10605874 (MoGene1.0st)   1440085_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041210
Ensembl peptide - ENSMUSP00000109463
NCBI entrez gene - 245527     See in Manteia.
MGI - MGI:2442860
RefSeq - XM_006528026
RefSeq - NM_001161432
RefSeq - NM_001161433
RefSeq - NM_175540
RefSeq - XM_006528025
RefSeq Peptide - NP_780749
RefSeq Peptide - NP_001154904
RefSeq Peptide - NP_001154905
swissprot - Q3KP88
swissprot - Q8BX35
Ensembl - ENSMUSG00000034457
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EDA2RENSGALG00000031094Gallus gallus
 EDA2RENSG00000131080Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9JLL3 / Tnfrsf19 / Tumor necrosis factor receptor superfamily member 19 / Q9NS68* / TNF receptor superfamily member 19*ENSMUSG0000006054834


Protein motifs (from Interpro)
Interpro ID Name
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR022319  Tumour necrosis factor receptor 27
 IPR034060  Tumor necrosis factor receptor 27, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009888 tissue development IBA
 biological_processGO:0012501 programmed cell death RCA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IBA
 biological_processGO:0046330 positive regulation of JNK cascade IBA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IGI
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lfngtm1Grid/Lfngtm1Grid,Rfngtm1Grid/Rfngtm1Grid
Genetic Background: involves: 129S1/SvImJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059327 Eda / O54693 / Ectodysplasin-A Ectodysplasin-A, membrane form Ectodysplasin-A, secreted form / Q92838* / ectodysplasin A*  / complex / reaction






 

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