ENSMUSG00000034872


Mus musculus

Features
Gene ID: ENSMUSG00000034872
  
Biological name :Gipc3
  
Synonyms : Gipc3 / PDZ domain-containing protein GIPC3 / Q8R5M0
  
Possible biological names infered from orthology : GIPC PDZ domain containing family member 3 / Q8TF64
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 81335265
Gene end: 81343266
  
Corresponding Affymetrix probe sets: 10371134 (MoGene1.0st)   1426150_at (Mouse Genome 430 2.0 Array)   1440731_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049236
NCBI entrez gene - 209047     See in Manteia.
MGI - MGI:2387006
RefSeq - NM_148951
RefSeq - XM_006513444
RefSeq Peptide - NP_683753
swissprot - Q8R5M0
Ensembl - ENSMUSG00000034872
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gipc3ENSDARG00000053074Danio rerio
 GIPC3ENSGALG00000028029Gallus gallus
 GIPC3ENSG00000179855Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gipc1 / Q9Z0G0 / PDZ domain-containing protein GIPC1 / O14908* / GIPC PDZ domain containing family member 1*ENSMUSG0000001943363
Gipc2 / Q9Z2H7 / PDZ domain-containing protein GIPC2 / Q8TF65* / GIPC PDZ domain containing family member 2*ENSMUSG0000003913157


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR017379  PDZ domain-containing protein GIPC1/2/3
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0031982 vesicle IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Ggnbp2tm1b(KOMP)Wtsi/Ggnbp2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ggnbp2tm1b(KOMP)Wtsi/Tcp

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ggnbp2tm1b(KOMP)Wtsi/Ggnbp2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Ggnbp2tm1b(KOMP)Wtsi/Tcp

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Adora2atm1Jfc/Adora2atm1Jfc
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

Allelic Composition: Gipc3tm1b(KOMP)Wtsi/Gipc3tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gipc3tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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