ENSMUSG00000034908


Mus musculus

Features
Gene ID: ENSMUSG00000034908
  
Biological name :Sidt2
  
Synonyms : Q8CIF6 / SID1 transmembrane family member 2 / Sidt2
  
Possible biological names infered from orthology : Q8NBJ9
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A5.2
Gene start: 45937857
Gene end: 45955258
  
Corresponding Affymetrix probe sets: 10593130 (MoGene1.0st)   1426940_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125660
Ensembl peptide - ENSMUSP00000125060
Ensembl peptide - ENSMUSP00000125273
Ensembl peptide - ENSMUSP00000044290
Ensembl peptide - ENSMUSP00000110220
Ensembl peptide - ENSMUSP00000124503
Ensembl peptide - ENSMUSP00000124577
Ensembl peptide - ENSMUSP00000124750
Ensembl peptide - ENSMUSP00000124945
Ensembl peptide - ENSMUSP00000125037
NCBI entrez gene - 214597     See in Manteia.
MGI - MGI:2446134
RefSeq - XM_006510147
RefSeq - NM_001289668
RefSeq - NM_172257
RefSeq - XM_006510141
RefSeq - XM_006510142
RefSeq - XM_006510143
RefSeq - XM_006510144
RefSeq - XM_006510145
RefSeq Peptide - NP_001276597
RefSeq Peptide - NP_758461
swissprot - Q3U1L8
swissprot - F6SV01
swissprot - F6TVH9
swissprot - F7B6N2
swissprot - F7CNB6
swissprot - F7DF36
swissprot - F7DFH5
swissprot - Q8CIF6
swissprot - F6SS13
swissprot - E0CXC7
Ensembl - ENSMUSG00000034908
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sidt2ENSDARG00000045976Danio rerio
 ENSGALG00000037273Gallus gallus
 ENSGALG00000030139Gallus gallus
 SIDT2ENSG00000149577Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sidt1 / Q6AXF6 / SID1 transmembrane family member 1 / Q9NXL6*ENSMUSG0000002269655


Protein motifs (from Interpro)
Interpro ID Name
 IPR025958  SID1 transmembrane family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0003323 type B pancreatic cell development IMP
 biological_processGO:0006401 RNA catabolic process IDA
 biological_processGO:0009749 response to glucose IMP
 biological_processGO:0033227 dsRNA transport IEA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0044342 type B pancreatic cell proliferation IMP
 biological_processGO:0050658 RNA transport IDA
 biological_processGO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035612 AP-2 adaptor complex binding IDA
 molecular_functionGO:0035650 AP-1 adaptor complex binding IDA
 molecular_functionGO:0051032 nucleic acid transmembrane transporter activity IDA
 molecular_functionGO:0051033 RNA transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0003564 abnormal insulin secretion "aberrant release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0003645 increased number of pancreatic beta cells "greater than normal number of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005217 abnormal pancreatic beta cell morphology "malformation of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
Show

Allelic Composition: Tnnt3tm2a(KOMP)Wtsi/Tnnt3tm2a(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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