ENSMUSG00000035142


Mus musculus

Features
Gene ID: ENSMUSG00000035142
  
Biological name :Nubpl
  
Synonyms : Iron-sulfur protein NUBPL / Nubpl / Q9CWD8
  
Possible biological names infered from orthology : nucleotide binding protein like / Q8TB37
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: C1
Gene start: 52097737
Gene end: 52312744
  
Corresponding Affymetrix probe sets: 10395684 (MoGene1.0st)   1429278_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044292
Ensembl peptide - ENSMUSP00000125177
NCBI entrez gene - 76826     See in Manteia.
MGI - MGI:1924076
RefSeq - NM_029760
RefSeq - XM_006516363
RefSeq Peptide - NP_084036
swissprot - F7D3P0
swissprot - Q9CWD8
Ensembl - ENSMUSG00000035142
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nubplENSDARG00000054821Danio rerio
 NUBPLENSGALG00000009983Gallus gallus
 NUBPLENSG00000151413Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nubp1 / Q9R060 / Cytosolic Fe-S cluster assembly factor NUBP1 / P53384* / nucleotide binding protein 1*ENSMUSG0000002250335


Protein motifs (from Interpro)
Interpro ID Name
 IPR000808  Mrp, conserved site
 IPR019591  Mrp/NBP35 ATP-binding protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR033756  Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly IEA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008174 decreased follicular B cell number "reduced number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes" [CL:0000843, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0010068 decreased red blood cell distribution width "lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", NCI:C64800 "NCI Thesaurus (Code C64800)"]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
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Allelic Composition: Nr6a1tm1b(EUCOMM)Wtsi/Nr6a1tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Nr6a1tm1b(EUCOMM)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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