ENSMUSG00000022503


Mus musculus

Features
Gene ID: ENSMUSG00000022503
  
Biological name :Nubp1
  
Synonyms : Cytosolic Fe-S cluster assembly factor NUBP1 / Nubp1 / Q9R060
  
Possible biological names infered from orthology : nucleotide binding protein 1 / P53384
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: A1
Gene start: 10411948
Gene end: 10424428
  
Corresponding Affymetrix probe sets: 10433494 (MoGene1.0st)   1418905_at (Mouse Genome 430 2.0 Array)   1418906_at (Mouse Genome 430 2.0 Array)   1430778_a_at (Mouse Genome 430 2.0 Array)   1457055_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023146
Ensembl peptide - ENSMUSP00000155550
NCBI entrez gene - 26425     See in Manteia.
MGI - MGI:1347073
RefSeq - NM_011955
RefSeq Peptide - NP_036085
swissprot - Q9R060
Ensembl - ENSMUSG00000022503
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nubp1ENSDARG00000055472Danio rerio
 NUBP1ENSGALG00000007241Gallus gallus
 NUBP1ENSG00000103274Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nubpl / Q9CWD8 / Iron-sulfur protein NUBPL / Q8TB37* / nucleotide binding protein like*ENSMUSG0000003514235


Protein motifs (from Interpro)
Interpro ID Name
 IPR000808  Mrp, conserved site
 IPR003593  AAA+ ATPase domain
 IPR019591  Mrp/NBP35 ATP-binding protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028601  Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35
 IPR033756  Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0010826 negative regulation of centrosome duplication IMP
 biological_processGO:0016226 iron-sulfur cluster assembly ISO
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0051642 centrosome localization IMP
 biological_processGO:0072697 protein localization to cell cortex IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding ISO
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

Allelic Composition: Nubp1m1Nisw/Nubp1tm1a(EUCOMM)Wtsi
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6N

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0001178 pulmonary hypoplasia "reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

Allelic Composition: Nubp1m1Nisw/Nubp1tm1a(EUCOMM)Wtsi
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6N

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0006382 abnormal lung epithelium morphology "any structural anomaly of the epithelial layer of the lung" [MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0011024 abnormal branching involved in lung morphogenesis "anomaly in the process in which the branched structure of the respiratory airway tree is generated and organized" [MGI:csmith]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Aw-27J/a
Genetic Background: C57BL/6J-Aw-27J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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