ENSG00000103274


Homo sapiens

Features
Gene ID: ENSG00000103274
  
Biological name :NUBP1
  
Synonyms : NUBP1 / nucleotide binding protein 1 / P53384
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.13
Gene start: 10743786
Gene end: 10769351
  
Corresponding Affymetrix probe sets: 203978_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000409654
Ensembl peptide - ENSP00000461723
Ensembl peptide - ENSP00000461746
Ensembl peptide - ENSP00000283027
Ensembl peptide - ENSP00000460288
NCBI entrez gene - 4682     See in Manteia.
OMIM - 600280
RefSeq - XM_017023252
RefSeq - NM_001278506
RefSeq - NM_001323594
RefSeq - NM_001323595
RefSeq - NM_001323596
RefSeq - NM_001323597
RefSeq - NM_002484
RefSeq Peptide - NP_001310524
RefSeq Peptide - NP_001310525
RefSeq Peptide - NP_001310526
RefSeq Peptide - NP_002475
RefSeq Peptide - NP_001265435
RefSeq Peptide - NP_001310523
swissprot - I3L531
swissprot - I3L3A0
swissprot - I3L518
swissprot - P53384
Ensembl - ENSG00000103274
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nubp1ENSDARG00000055472Danio rerio
 NUBP1ENSGALG00000007241Gallus gallus
 Nubp1ENSMUSG00000022503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NUBPL / Q8TB37 / nucleotide binding protein likeENSG0000015141333


Protein motifs (from Interpro)
Interpro ID Name
 IPR000808  Mrp, conserved site
 IPR003593  AAA+ ATPase domain
 IPR019591  Mrp/NBP35 ATP-binding protein
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028601  Cytosolic Fe-S cluster assembly factor NUBP1/Nbp35
 IPR033756  Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IMP
 biological_processGO:0010826 negative regulation of centrosome duplication IEA
 biological_processGO:0016049 cell growth IMP
 biological_processGO:0016226 iron-sulfur cluster assembly IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0051642 centrosome localization IEA
 biological_processGO:0072697 protein localization to cell cortex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IDA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Cytosolic iron-sulfur cluster assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000095906 NUBP2 / Q9Y5Y2 / nucleotide binding protein 2  / complex
 ENSG00000103274 NUBP1 / P53384 / nucleotide binding protein 1  / complex






 

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