ENSMUSG00000035509


Mus musculus

Features
Gene ID: ENSMUSG00000035509
  
Biological name :Fbxl21
  
Synonyms : Fbxl21 / Mus musculus F-box and leucine-rich repeat protein 21 (Fbxl21), transcript variant 2, mRNA. / Q8BFZ4
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: B1
Gene start: 56522472
Gene end: 56537898
  
Corresponding Affymetrix probe sets: 10405576 (MoGene1.0st)   1457232_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114329
Ensembl peptide - ENSMUSP00000115636
Ensembl peptide - ENSMUSP00000035248
Ensembl peptide - ENSMUSP00000112518
Ensembl peptide - ENSMUSP00000112714
NCBI entrez gene - 213311     See in Manteia.
MGI - MGI:2442921
RefSeq - XM_011244506
RefSeq - XM_006517206
RefSeq - XM_011244507
RefSeq - NM_001346732
RefSeq - NM_178674
RefSeq - XM_017315478
RefSeq Peptide - NP_848789
RefSeq Peptide - NP_001333661
swissprot - Q8BFZ4
swissprot - D6RE27
swissprot - A0A0R4J1M5
swissprot - G3X9Y3
Ensembl - ENSMUSG00000035509
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl3lENSDARG00000037738Danio rerio
 FBXL21ENSGALG00000006327Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fbxl3 / Q8C4V4 / F-box/LRR-repeat protein 3 / Q9UKT7* / F-box and leucine rich repeat protein 3*ENSMUSG0000002212468


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043153 entrainment of circadian clock by photoperiod IMP
 biological_processGO:0048511 rhythmic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005645 abnormal hypothalamus physiology "anomalous function of the ventral and medial region of the diencephalon forming the walls of the ventral half of the third ventricle, which is normally involved in the functions of the autonomic (visceral motor) nervous system and, through its vascular link with the anterior lobe of the pituitary gland, in endocrine mechanisms" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fbxl21Psttm/Fbxl21Psttm
Genetic Background: involves: C57BL/6J

 MP:0020414 abnormal fibroblast physiology "any functional anomaly in the cellular physiological processes carried out by a fibroblast cell population" [mgi:anna]
Show

Allelic Composition: Fbxl21Psttm/Fbxl21Psttm
Genetic Background: involves: C57BL/6J

 MP:0020467 abnormal circadian behavior "any anomaly in the specific behavior of an organism that recurs with a regularity of approximately 24 hours" [GO:0048512]
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Allelic Composition: Fbxl3tm1Kei/Fbxl3tm1Kei
Genetic Background: B6.Cg-Fbxl3tm1Kei

Allelic Composition: Fbxl21tm1Kei/Fbxl21tm1Kei,Fbxl3tm1Kei/Fbxl3tm1Kei
Genetic Background: B6.Cg-Fbxl21tm1Kei Fbxl3tm1Kei

 MP:0020470 shortened circadian behavior period "decrease in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb]
Show

Allelic Composition: Apctm2.1Cip/Apctm2.1Cip
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

Allelic Composition: Fbxl21Psttm/Fbxl21Psttm
Genetic Background: involves: C57BL/6J

Allelic Composition: Fbxl21Psttm/Fbxl21Psttm
Genetic Background: involves: BTBR * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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