ENSMUSG00000035798


Mus musculus

Features
Gene ID: ENSMUSG00000035798
  
Biological name :Zdhhc17
  
Synonyms : Q80TN5 / Zdhhc17 / zinc finger, DHHC domain containing 17
  
Possible biological names infered from orthology : Q8IUH5 / zinc finger DHHC-type containing 17
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D1
Gene start: 110941780
Gene end: 111010140
  
Corresponding Affymetrix probe sets: 10372383 (MoGene1.0st)   10372385 (MoGene1.0st)   1434397_at (Mouse Genome 430 2.0 Array)   1447656_at (Mouse Genome 430 2.0 Array)   1455986_at (Mouse Genome 430 2.0 Array)   1458084_at (Mouse Genome 430 2.0 Array)   1458363_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043279
Ensembl peptide - ENSMUSP00000151754
Ensembl peptide - ENSMUSP00000151491
Ensembl peptide - ENSMUSP00000151330
NCBI entrez gene - 320150     See in Manteia.
MGI - MGI:2445110
RefSeq - XM_006513762
RefSeq - NM_172554
RefSeq - XM_006513761
RefSeq Peptide - NP_766142
swissprot - A0A1W2P7M2
swissprot - Q80TN5
swissprot - A0A1W2P6S3
swissprot - A0A1W2P760
Ensembl - ENSMUSG00000035798
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zdhhc17ENSDARG00000070441Danio rerio
 ZDHHC17ENSGALG00000010253Gallus gallus
 Q8IUH5ENSG00000186908Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CWU2 / Zdhhc13 / zinc finger, DHHC domain containing 13 / Q8IUH4* / zinc finger DHHC-type containing 13*ENSMUSG0000003047145
Q8VC90 / Zdhhc12 / zinc finger, DHHC domain containing 12 / Q96GR4* / zinc finger DHHC-type containing 12*ENSMUSG0000001533512


Protein motifs (from Interpro)
Interpro ID Name
 IPR001594  Palmitoyltransferase, DHHC domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR030289  Palmitoyltransferase ZDHHC17
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018345 protein palmitoylation IEA
 biological_processGO:0042953 lipoprotein transport IEA
 biological_processGO:1903830 magnesium ion transmembrane transport IEA
 cellular_componentGO:0000139 Golgi membrane ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0030660 Golgi-associated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0015095 magnesium ion transmembrane transporter activity IEA
 molecular_functionGO:0016409 palmitoyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0019706 protein-cysteine S-palmitoyltransferase activity ISO
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0001522 impaired swimming "reduced ability or inability to swim" [J:45446, J:39081]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002175 low brain weight "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0002574 increased vertical activity "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0004077 abnormal striatum morphology "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0008026 abnormal brain white matter morphology "any structural anomaly of the regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0008948 decreased neuron number "fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0009538 abnormal synapse morphology "any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]
Show

Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0009848 increased horizontal stereotypic behavior "increase in the frequency of repetitive rearings (greater than one per second)" [PMID:19720087]
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Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0009849 increased vertical stereotypic behavior "increase in the frequency of vertical crossings (greater than one per second)" [PMID:19720087]
Show

Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0012468 decreased striatum area "reduced size of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [ISBN:0838580343, MGI:csmith]
Show

Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

 MP:0020083 decreased hippocampus volume "decrease from the average range of the hippocampus volume compared to normal" [GOC:NV]
Show

Allelic Composition: Gt(ROSA)26Sortm1Lrsn/Gt(ROSA)26Sor+,Prkntm1Roo/Prkntm1Roo,Slc6a3tm1(cre)Lrsn/Slc6a3+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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