ENSMUSG00000035941


Mus musculus

Features
Gene ID: ENSMUSG00000035941
  
Biological name :Ibtk
  
Synonyms : Ibtk / Inhibitor of Bruton tyrosine kinase / Q6ZPR6
  
Possible biological names infered from orthology : Q9P2D0
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.1
Gene start: 85687360
Gene end: 85749334
  
Corresponding Affymetrix probe sets: 10595407 (MoGene1.0st)   1434282_at (Mouse Genome 430 2.0 Array)   1439285_at (Mouse Genome 430 2.0 Array)   1454905_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041145
Ensembl peptide - ENSMUSP00000139424
NCBI entrez gene - 108837     See in Manteia.
MGI - MGI:1918677
RefSeq - XM_006510766
RefSeq - NM_001081282
RefSeq - XM_006510765
RefSeq Peptide - NP_001074751
swissprot - Q6ZPR6
swissprot - A0A087WNN3
Ensembl - ENSMUSG00000035941
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ibtkENSDARG00000074424Danio rerio
 IBTKENSGALG00000015864Gallus gallus
 IBTKENSG00000005700Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mycbp2 / MYC binding protein 2, E3 ubiquitin protein ligase / O75592*ENSMUSG0000003300422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR002110  Ankyrin repeat
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0051209 release of sequestered calcium ion into cytosol IEA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030292 protein tyrosine kinase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009333 abnormal splenocyte physiology "any functional anomaly of a cell of the spleen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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