ENSMUSG00000036199


Mus musculus

Features
Gene ID: ENSMUSG00000036199
  
Biological name :Ndufa13
  
Synonyms : NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 / Ndufa13 / Q9ERS2
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase subunit A13 / Q9P0J0
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.3
Gene start: 69894180
Gene end: 69902558
  
Corresponding Affymetrix probe sets: 10579119 (MoGene1.0st)   1430713_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105796
NCBI entrez gene - 67184     See in Manteia.
MGI - MGI:1914434
RefSeq - NM_023312
RefSeq - XM_017312943
RefSeq Peptide - NP_075801
swissprot - Q9ERS2
Ensembl - ENSMUSG00000036199
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039212Gallus gallus
 Q9P0J0ENSG00000186010Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009346  GRIM-19


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly IEA
 biological_processGO:0035458 cellular response to interferon-beta IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0045039 protein import into mitochondrial inner membrane IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IDA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005746 mitochondrial respiratory chain IEA
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003954 NADH dehydrogenase activity IEA
 molecular_functionGO:0005524 ATP binding TAS
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001696 failure to gastrulate "inability to differentiate and invaginate the primary germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:34458]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0002718 abnormal inner cell mass "malformed or absent cells of the blastocyst that develop into the body of the embryo" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0005028 abnormal trophectoderm "malformed outermost layer of cells in the blastodermic vesicle, which will contact the endometrium and take part in establishing the embryo s means of nutrition" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0011633 abnormal mitochondrial shape "any anomaly in the characteristic surface outline or contour of a mitochondria" [MGI:csmith]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
Show

Allelic Composition: Timp3tm1Rkho/Timp3tm1Rkho
Genetic Background: B6.129-Timp3tm1Rkho

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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