ENSMUSG00000036442


Mus musculus

Features
Gene ID: ENSMUSG00000036442
  
Biological name :Thap11
  
Synonyms : Q9JJD0 / Thap11 / THAP domain-containing protein 11
  
Possible biological names infered from orthology : Q96EK4 / THAP domain containing 11
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: D3
Gene start: 105855132
Gene end: 105856950
  
Corresponding Affymetrix probe sets: 10574897 (MoGene1.0st)   1416428_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048994
NCBI entrez gene - 59016     See in Manteia.
MGI - MGI:1930964
RefSeq - NM_021513
RefSeq Peptide - NP_067488
swissprot - Q9JJD0
Ensembl - ENSMUSG00000036442
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6TGZ4ENSDARG00000036055Danio rerio
 THAP11ENSGALG00000030657Gallus gallus
 Q96EK4ENSG00000168286Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006612  THAP-type zinc finger
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0045171 intercellular bridge IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Faslpr/Faslpr
Genetic Background: C3.MRL-Faslpr

Allelic Composition: Thap11tm1.1Tpz/Thap11tm1.1Tpz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
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Allelic Composition: Thap11tm1.1Tpz/Thap11tm1.1Tpz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0012114 absent inner cell mass proliferation 
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Allelic Composition: Thap11tm1.1Tpz/Thap11tm1.1Tpz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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