ENSMUSG00000037062


Mus musculus

Features
Gene ID: ENSMUSG00000037062
  
Biological name :Sh3glb1
  
Synonyms : Endophilin-B1 / Q9JK48 / Sh3glb1
  
Possible biological names infered from orthology : Q9Y371 / SH3 domain containing GRB2 like, endophilin B1
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: H2
Gene start: 144683678
Gene end: 144720335
  
Corresponding Affymetrix probe sets: 10502537 (MoGene1.0st)   1418010_a_at (Mouse Genome 430 2.0 Array)   1418011_a_at (Mouse Genome 430 2.0 Array)   1418012_at (Mouse Genome 430 2.0 Array)   1435631_x_at (Mouse Genome 430 2.0 Array)   1455385_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143312
Ensembl peptide - ENSMUSP00000142716
Ensembl peptide - ENSMUSP00000143433
Ensembl peptide - ENSMUSP00000143031
Ensembl peptide - ENSMUSP00000129800
Ensembl peptide - ENSMUSP00000142626
NCBI entrez gene - 54673     See in Manteia.
MGI - MGI:1859730
RefSeq - XM_006501716
RefSeq - XM_006501718
RefSeq - XM_006501717
RefSeq - NM_001282037
RefSeq - NM_001282042
RefSeq - NM_019464
RefSeq Peptide - NP_001268966
RefSeq Peptide - NP_001268971
RefSeq Peptide - NP_062337
swissprot - Q9JK48
swissprot - A0A0G2JF57
swissprot - A0A0G2JE45
swissprot - A0A0G2JEC4
Ensembl - ENSMUSG00000037062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3glb1aENSDARG00000045294Danio rerio
 sh3glb1bENSDARG00000010956Danio rerio
 Q5ZIR1ENSGALG00000006284Gallus gallus
 Q9Y371ENSG00000097033Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R3V5 / Sh3glb2 / SH3-domain GRB2-like endophilin B2 / Q9NR46* / SH3 domain containing GRB2 like, endophilin B2*ENSMUSG0000002686062
Q62419 / Sh3gl1 / SH3-domain GRB2-like 1 / Q99961* / SH3 domain containing GRB2 like 1, endophilin A2*ENSMUSG0000000320024
Q62420 / Sh3gl2 / SH3-domain GRB2-like 2 / Q99962* / SH3 domain containing GRB2 like 2, endophilin A1*ENSMUSG0000002848824
Sh3gl3 / endophilin-A3 isoform 3 / Q99963* / SH3 domain containing GRB2 like 3, endophilin A3*ENSMUSG0000003063823


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR004148  BAR domain
 IPR027267  AH/BAR domain superfamily
 IPR028503  Endophilin-B1
 IPR035695  Endophilin-B1, BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006654 phosphatidic acid biosynthetic process IDA
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0008654 phospholipid biosynthetic process IDA
 biological_processGO:0010508 positive regulation of autophagy IMP
 biological_processGO:0031647 regulation of protein stability ISO
 biological_processGO:0032461 positive regulation of protein oligomerization ISO
 biological_processGO:0032465 regulation of cytokinesis ISO
 biological_processGO:0032801 receptor catabolic process ISO
 biological_processGO:0034198 cellular response to amino acid starvation ISO
 biological_processGO:0042149 cellular response to glucose starvation ISO
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IMP
 biological_processGO:0048102 autophagic cell death IMP
 biological_processGO:0051084 "de novo" posttranslational protein folding IDA
 biological_processGO:0051259 protein complex oligomerization ISO
 biological_processGO:0090148 membrane fission ISO
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway IMP
 biological_processGO:1903527 positive regulation of membrane tubulation ISO
 biological_processGO:1903778 protein localization to vacuolar membrane IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 biological_processGO:2000786 positive regulation of autophagosome assembly IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005740 mitochondrial envelope ISO
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IC
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0030496 midbody ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005504 fatty acid binding IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042171 lysophosphatidic acid acyltransferase activity IDA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0013502 decreased fibroblast apoptosis "reduction in the timing or the number of fibroblast cells undergoing programmed cell death" [MGI:csmith]
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Allelic Composition: Spi1tm1Sing/Spi1+,Spibtm1Mcs/Spibtm1Mcs
Genetic Background: involves: 129S/SvEv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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