ENSMUSG00000037318


Mus musculus

Features
Gene ID: ENSMUSG00000037318
  
Biological name :Traf3ip3
  
Synonyms : TRAF3 interacting protein 3 / Traf3ip3
  
Possible biological names infered from orthology : Q9Y228
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H6
Gene start: 193175453
Gene end: 193201703
  
Corresponding Affymetrix probe sets: 10361215 (MoGene1.0st)   1434573_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141358
Ensembl peptide - ENSMUSP00000142321
Ensembl peptide - ENSMUSP00000141938
Ensembl peptide - ENSMUSP00000141698
Ensembl peptide - ENSMUSP00000141669
Ensembl peptide - ENSMUSP00000141661
Ensembl peptide - ENSMUSP00000040977
NCBI entrez gene - 215243     See in Manteia.
MGI - MGI:2441706
RefSeq - NM_153137
RefSeq Peptide - NP_694777
swissprot - A0A0A6YWR4
swissprot - A0A0A6YY84
swissprot - G3X949
swissprot - A0A0A6YW19
swissprot - A0A0A6YXD0
swissprot - A0A0A6YWS1
Ensembl - ENSMUSG00000037318
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR847543.1ENSDARG00000086708Danio rerio
 TRAF3IP3ENSGALG00000001373Gallus gallus
 Q9Y228ENSG00000009790Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Slmap / Q3URD3 / Sarcolemmal membrane-associated protein / Q14BN4* / sarcolemma associated protein*ENSMUSG0000002187022
Ccdc136 / Mus musculus coiled-coil domain containing 136 (Ccdc136), transcript variant 4, mRNA. / Q96JN2* / coiled-coil domain containing 136*ENSMUSG0000002976914


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000221 decreased WBC count "fewer than normal numbers of WBCs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0000715 decreased thymocyte number "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0002145 abnormal T lymphocyte development "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0004974 decreased regulatory T cell number "reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0005018 decreased T cell number "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0005091 increased double-positive T cell count "greater than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0008346 increased gamma-delta T cell number "greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0010836 decreased CD4-positive, alpha-beta memory T cell number "reduced number of CD4-positive, alpha-beta long-lived T cells with the phenotype CD45RO-positive and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high" [CL:0000897, GO_REF:0000031, GOC:add, GOC:tfm, http://www.immgen.org/index_content.html, ISBN:0781735149]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

 MP:0010839 decreased CD8-positive, alpha-beta memory T cell number "decreased number of CD8-positive, alpha-beta T cells with memory phenotype indicated by being CD45RO and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high" [CL:0000909, GO_REF:0000031, GOC:tfm, PMID:20146720]
Show

Allelic Composition: Pnkptm1.1Pmc/Pnkptm1.1Pmc,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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