ENSMUSG00000037408


Mus musculus

Features
Gene ID: ENSMUSG00000037408
  
Biological name :Cnnm4
  
Synonyms : Cnnm4 / Metal transporter CNNM4 / Q69ZF7
  
Possible biological names infered from orthology : cyclin and CBS domain divalent metal cation transport mediator 4 / Q6P4Q7
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: B
Gene start: 36471620
Gene end: 36508764
  
Corresponding Affymetrix probe sets: 10345482 (MoGene1.0st)   1421635_at (Mouse Genome 430 2.0 Array)   1431233_at (Mouse Genome 430 2.0 Array)   1434847_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121317
NCBI entrez gene - 94220     See in Manteia.
MGI - MGI:2151060
RefSeq - NM_033570
RefSeq Peptide - NP_291048
swissprot - Q69ZF7
Ensembl - ENSMUSG00000037408
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNNM4ENSG00000158158Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cnnm2 / Q3TWN3 / Metal transporter CNNM2 / Q9H8M5* / cyclin and CBS domain divalent metal cation transport mediator 2*ENSMUSG0000006410563
Cnnm1 / Q0GA42 / Metal transporter CNNM1 / Q9NRU3* / cyclin and CBS domain divalent metal cation transport mediator 1*ENSMUSG0000002518946
Cnnm3 / Q32NY4 / Mus musculus cyclin M3 (Cnnm3), transcript variant 3, mRNA. / Q8NE01* / cyclin and CBS domain divalent metal cation transport mediator 3*ENSMUSG0000000113839


Protein motifs (from Interpro)
Interpro ID Name
 IPR000644  CBS domain
 IPR002550  CNNM, transmembrane domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0010960 magnesium ion homeostasis IMP
 biological_processGO:0015693 magnesium ion transport IMP
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0055065 metal ion homeostasis IEA
 biological_processGO:0070166 enamel mineralization IMP
 biological_processGO:1903830 magnesium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0015081 sodium ion transmembrane transporter activity IDA
 molecular_functionGO:0015095 magnesium ion transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0002576 abnormal enamel morphology "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0003868 abnormal feces composition "increase or decrease in the amount of compunds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0010093 decreased circulating magnesium level "a reduction in the blood concentration of magnesium" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0011436 decreased urine magnesium level "lower than normal amount of magnesium in the urine" [MGI:anna]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0013129 abnormal tooth color "anomaly in the color and shading of the teeth, which normally present in shades of white" [MGI:Ahmad_Retha]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

 MP:0030450 abnormal enamel mineralization "anomaly in the process by which calcium salts, mainly carbonated hydroxyapatite, are deposited into the dental enamel" [GO:0070166]
Show

Allelic Composition: Ednrbs-l/Ednrbs-l
Genetic Background: involves: C57BL/6J * SSL/Le

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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