ENSMUSG00000064105


Mus musculus

Features
Gene ID: ENSMUSG00000064105
  
Biological name :Cnnm2
  
Synonyms : Cnnm2 / Metal transporter CNNM2 / Q3TWN3
  
Possible biological names infered from orthology : cyclin and CBS domain divalent metal cation transport mediator 2 / Q9H8M5
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 46761596
Gene end: 46878795
  
Corresponding Affymetrix probe sets: 10463716 (MoGene1.0st)   1423475_at (Mouse Genome 430 2.0 Array)   1451007_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076850
Ensembl peptide - ENSMUSP00000096972
NCBI entrez gene - 94219     See in Manteia.
MGI - MGI:2151054
RefSeq - NM_001102471
RefSeq - NM_033569
RefSeq Peptide - NP_001095941
RefSeq Peptide - NP_291047
swissprot - Q3TWN3
Ensembl - ENSMUSG00000064105
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnnm4aENSDARG00000102380Danio rerio
 CNNM2ENSGALG00000008160Gallus gallus
 CNNM2ENSG00000148842Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cnnm4 / Q69ZF7 / Metal transporter CNNM4 / Q6P4Q7* / cyclin and CBS domain divalent metal cation transport mediator 4*ENSMUSG0000003740856
Cnnm1 / Q0GA42 / Metal transporter CNNM1 / Q9NRU3* / cyclin and CBS domain divalent metal cation transport mediator 1*ENSMUSG0000002518948
Cnnm3 / Q32NY4 / Mus musculus cyclin M3 (Cnnm3), transcript variant 3, mRNA. / Q8NE01* / cyclin and CBS domain divalent metal cation transport mediator 3*ENSMUSG0000000113835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000644  CBS domain
 IPR002550  CNNM, transmembrane domain
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0010960 magnesium ion homeostasis ISO
 biological_processGO:0015693 magnesium ion transport IDA
 biological_processGO:1903830 magnesium ion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0015095 magnesium ion transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Ckap4tm1b(EUCOMM)Hmgu/Ckap4+
Genetic Background: C57BL/6N-Ckap4tm1b(EUCOMM)Hmgu/Bay

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Ckap4tm1b(EUCOMM)Hmgu/Ckap4+
Genetic Background: C57BL/6N-Ckap4tm1b(EUCOMM)Hmgu/Bay

 MP:0013294 prenatal lethality prior to heart atrial septation "death prior to the completion of heart atrial septation (Mus: E14.5-15.5)" [MGI:smb]
Show

Allelic Composition: Ckap4tm1b(EUCOMM)Hmgu/Ckap4+
Genetic Background: C57BL/6N-Ckap4tm1b(EUCOMM)Hmgu/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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