ENSMUSG00000037697


Mus musculus

Features
Gene ID: ENSMUSG00000037697
  
Biological name :Ddhd1
  
Synonyms : Ddhd1 / phospholipase DDHD1 isoform 4
  
Possible biological names infered from orthology : DDHD domain containing 1 / Q8NEL9
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C1
Gene start: 45588467
Gene end: 45658143
  
Corresponding Affymetrix probe sets: 10419240 (MoGene1.0st)   1427289_at (Mouse Genome 430 2.0 Array)   1445438_at (Mouse Genome 430 2.0 Array)   1454070_a_at (Mouse Genome 430 2.0 Array)   1455321_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121837
Ensembl peptide - ENSMUSP00000133358
Ensembl peptide - ENSMUSP00000154065
Ensembl peptide - ENSMUSP00000050088
Ensembl peptide - ENSMUSP00000084577
Ensembl peptide - ENSMUSP00000107459
Ensembl peptide - ENSMUSP00000118848
NCBI entrez gene - 114874     See in Manteia.
MGI - MGI:2150302
RefSeq - NM_176845
RefSeq - NM_001284399
RefSeq - NM_001042719
RefSeq - NM_001039106
RefSeq Peptide - NP_789815
RefSeq Peptide - NP_001034195
RefSeq Peptide - NP_001036184
RefSeq Peptide - NP_001271328
swissprot - F8WHP5
swissprot - E9QQ38
swissprot - D6RH62
swissprot - G3UWN4
swissprot - G3UVX0
swissprot - F8WIJ5
Ensembl - ENSMUSG00000037697
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddhd1aENSDARG00000086808Danio rerio
 ddhd1bENSDARG00000037042Danio rerio
 DDHD1ENSGALG00000012426Gallus gallus
 DDHD1ENSG00000100523Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sec23ip / Sec23 interacting protein / Q9Y6Y8*ENSMUSG0000005531920
Ddhd2 / Q80Y98 / Phospholipase DDHD2 / O94830* / DDHD domain containing 2*ENSMUSG0000006131319


Protein motifs (from Interpro)
Interpro ID Name
 IPR004177  DDHD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0090141 positive regulation of mitochondrial fission IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of PA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000062 increased bone density "increased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Bmi1tm1.1Lees/Bmi1tm1.1Lees
Genetic Background: involves: 129S4/SvJae * C57BL/6

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0002674 abnormal sperm motility "anomalies in the mobility of the spermatozoa" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0004151 hypoferremia "less than the normal concentration of this metallic element in the blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0005578 teratozoospermia "presence of malformed spermatozoa in the semen; malformations include the physical bending of the sperm to produce kinks or bends" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddhd1tm1b(KOMP)Katn/Ddhd1tm1b(KOMP)Katn
Genetic Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

 MP:0010844 increased effector memory CD4-positive, alpha-beta T cell number "increased number of CD4-positive, alpha-beta memory T cells with the phenotype CCR7-negative, CD127-positive, CD45RO-positive, and CD25-negative" [CL:0000905, GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm]
Show

Allelic Composition: Dixdc1tm1.1(KOMP)Vlcg/Dixdc1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Dixdc1tm1.1(KOMP)Vlcg/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr