ENSMUSG00000037722


Mus musculus

Features
Gene ID: ENSMUSG00000037722
  
Biological name :Gnpnat1
  
Synonyms : glucosamine-phosphate N-acetyltransferase 1 / Gnpnat1 / Q9JK38
  
Possible biological names infered from orthology : Q96EK6
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C1
Gene start: 45376334
Gene end: 45404913
  
Corresponding Affymetrix probe sets: 10419216 (MoGene1.0st)   10460108 (MoGene1.0st)   1423156_at (Mouse Genome 430 2.0 Array)   1423157_at (Mouse Genome 430 2.0 Array)   1423158_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154780
Ensembl peptide - ENSMUSP00000042860
Ensembl peptide - ENSMUSP00000154025
Ensembl peptide - ENSMUSP00000154084
Ensembl peptide - ENSMUSP00000154138
Ensembl peptide - ENSMUSP00000154299
Ensembl peptide - ENSMUSP00000154382
Ensembl peptide - ENSMUSP00000154590
Ensembl peptide - ENSMUSP00000154777
NCBI entrez gene - 54342     See in Manteia.
MGI - MGI:1858963
RefSeq - XM_006519276
RefSeq - NM_019425
RefSeq - XM_006519274
RefSeq - XM_006519275
RefSeq Peptide - NP_062298
swissprot - Q9JK38
Ensembl - ENSMUSG00000037722
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gnpnat1ENSDARG00000039892Danio rerio
 GNPNAT1ENSGALG00000012414Gallus gallus
 Q96EK6ENSG00000100522Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000182  GNAT domain
 IPR016181  Acyl-CoA N-acyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006041 glucosamine metabolic process IEA
 biological_processGO:0006044 N-acetylglucosamine metabolic process IEA
 biological_processGO:0006048 UDP-N-acetylglucosamine biosynthetic process TAS
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IDA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004343 glucosamine 6-phosphate N-acetyltransferase activity IDA
 molecular_functionGO:0008080 N-acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0048029 monosaccharide binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of UDP-N-acetyl-glucosamine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000352 decreased cell proliferation "less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0001683 absent mesoderm "missing or failure to differentiate the middle primary germ layer " [J:40594]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0002584 small ectoplacental cone 
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0003087 absent allantois "missing fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0005030 absent amnion "missing innermost of the extraembryonic membranes" [dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0009593 absent chorion "absence of the outermost extraembryonic membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0011096 complete embryonic lethality before somite formation "death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]
Show

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037722 Q9JK38 / Gnpnat1 / glucosamine-phosphate N-acetyltransferase 1 / Q96EK6*  / complex






 

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