ENSMUSG00000037731


Mus musculus

Features
Gene ID: ENSMUSG00000037731
  
Biological name :Themis2
  
Synonyms : Protein THEMIS2 / Q91YX0 / Themis2
  
Possible biological names infered from orthology : Q5TEJ8 / thymocyte selection associated family member 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.3
Gene start: 132781843
Gene end: 132796387
  
Corresponding Affymetrix probe sets: 10516966 (MoGene1.0st)   1427041_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036945
NCBI entrez gene - 230787     See in Manteia.
MGI - MGI:2446213
RefSeq - NM_001033308
RefSeq - XM_011250230
RefSeq Peptide - NP_001028480
swissprot - Q91YX0
Ensembl - ENSMUSG00000037731
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 themis2ENSDARG00000058964Danio rerio
 THEMIS2ENSGALG00000000731Gallus gallus
 Q5TEJ8ENSG00000130775Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BGW0 / Themis / thymocyte selection associated / Q8N1K5*ENSMUSG0000004910930
Q9CU24 / Themis3 / Protein THEMIS3 ENSMUSG0000002410519


Protein motifs (from Interpro)
Interpro ID Name
 IPR025946  CABIT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0050852 T cell receptor signaling pathway IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

 MP:0005628 decreased circulating potassium level "less than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Kmt5btm1a(KOMP)Wtsi/Kmt5btm1a(KOMP)Wtsi
Genetic Background: B6JTyr;B6N-Kmt5btm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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