ENSMUSG00000037851


Mus musculus

Features
Gene ID: ENSMUSG00000037851
  
Biological name :Iars
  
Synonyms : Iars / Isoleucine--tRNA ligase, cytoplasmic / Q8BU30
  
Possible biological names infered from orthology : isoleucyl-tRNA synthetase / P41252
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 49682100
Gene end: 49734267
  
Corresponding Affymetrix probe sets: 10345025 (MoGene1.0st)   10405094 (MoGene1.0st)   1426705_s_at (Mouse Genome 430 2.0 Array)   1452154_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000130204
Ensembl peptide - ENSMUSP00000132082
Ensembl peptide - ENSMUSP00000048096
Ensembl peptide - ENSMUSP00000126806
Ensembl peptide - ENSMUSP00000130058
NCBI entrez gene - 105148     See in Manteia.
MGI - MGI:2145219
RefSeq - NM_172015
RefSeq - XM_006516826
RefSeq Peptide - NP_742012
swissprot - E9Q866
swissprot - Q8BU30
swissprot - F6Q6R1
Ensembl - ENSMUSG00000037851
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 iarsENSDARG00000007955Danio rerio
 IARSENSGALG00000004813Gallus gallus
 IARSENSG00000196305Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002300  Aminoacyl-tRNA synthetase, class Ia
 IPR002301  Isoleucine-tRNA ligase
 IPR009008  Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR013155  Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR023586  Isoleucine-tRNA ligase, type 2
 IPR033709  Isoleucyl tRNA synthetase type 2, anticodon-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006428 isoleucyl-tRNA aminoacylation IDA
 biological_processGO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0017101 aminoacyl-tRNA synthetase multienzyme complex IDA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002161 aminoacyl-tRNA editing activity IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004822 isoleucine-tRNA ligase activity IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0051020 GTPase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr