ENSMUSG00000038248


Mus musculus

Features
Gene ID: ENSMUSG00000038248
  
Biological name :Sobp
  
Synonyms : Q0P5V2 / Sine oculis-binding protein homolog / Sobp
  
Possible biological names infered from orthology : A7XYQ1
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B2
Gene start: 43002500
Gene end: 43174530
  
Corresponding Affymetrix probe sets: 10368918 (MoGene1.0st)   1427542_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000040072
NCBI entrez gene - 109205     See in Manteia.
MGI - MGI:1924427
RefSeq - NM_175407
RefSeq - XM_017313763
RefSeq Peptide - NP_780616
swissprot - Q0P5V2
Ensembl - ENSMUSG00000038248
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sobpaENSDARG00000054253Danio rerio
 SOBPENSGALG00000043047Gallus gallus
 SOBPENSG00000112320Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026092  Retinoic acid-induced protein 2/sine oculis-binding protein homologue


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0042472 inner ear morphogenesis IMP
 biological_processGO:0050890 cognition IEA
 biological_processGO:0090102 cochlea development IMP
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0032184 SUMO polymer binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000031 abnormal cochlea morphology "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0001394 circling "repeated, compulsive movement in a circle; often associated with inner ear defects" [MGI:CLS, J:61295]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

Allelic Composition: Sobpjc-2J/Sobpjc-2J
Genetic Background: B6(129S2)-Sobpjc-2J/J

 MP:0001395 bi-directional circling "circling behavior exhibited in both clockwise and counterclockwise directions" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0004737 absent distortion product otoacoustic emissions "failure to create mechanical distortions in the inner ear when two primary tones are presented, indicating failure of outer hair cells to amplify basilar membrane motion" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0004813 absent linear vestibular evoked potential "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0008307 short scala media "reduced length of the spirally arranged membranous tube suspended within the cochlea, lying between and separating the scala vestibuli and scala tympani" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Grid2Lc/Grid2+
Genetic Background: B6CBACa Aw-J/A-Grid2Lc/J

Allelic Composition: Sobpjc-2J/Sobpjc-2J
Genetic Background: B6(129S2)-Sobpjc-2J/J

 MP:0011968 decreased threshold for auditory brainstem response "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith]
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Allelic Composition: Gja5tm1Paul/Gja5+
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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