ENSMUSG00000038383


Mus musculus

Features
Gene ID: ENSMUSG00000038383
  
Biological name :Pigu
  
Synonyms : phosphatidylinositol glycan anchor biosynthesis, class U / Pigu / Q8K358
  
Possible biological names infered from orthology : Q9H490
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H1
Gene start: 155278243
Gene end: 155357430
  
Corresponding Affymetrix probe sets: 10488830 (MoGene1.0st)   1427466_at (Mouse Genome 430 2.0 Array)   1427928_s_at (Mouse Genome 430 2.0 Array)   1439350_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076816
Ensembl peptide - ENSMUSP00000126236
NCBI entrez gene - 228812     See in Manteia.
MGI - MGI:3039607
RefSeq - XM_006499333
RefSeq - NM_001004721
RefSeq Peptide - NP_001004721
swissprot - Q3TAA8
swissprot - Q8K358
Ensembl - ENSMUSG00000038383
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 piguENSDARG00000075530Danio rerio
 PIGUENSGALG00000001219Gallus gallus
 PIGUENSG00000101464Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009600  GPI transamidase subunit PIG-U


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006506 GPI anchor biosynthetic process ISO
 biological_processGO:0016255 attachment of GPI anchor to protein ISO
 biological_processGO:0046425 regulation of JAK-STAT cascade ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042765 GPI-anchor transamidase complex ISO
 molecular_functionGO:0003923 GPI-anchor transamidase activity ISO
 molecular_functionGO:0034235 GPI anchor binding ISO


Pathways (from Reactome)
Pathway description
Attachment of GPI anchor to uPAR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001891 hydroencephaly "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Padi6tm1b(KOMP)Wtsi/Padi6tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Padi6tm1b(KOMP)Wtsi/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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