ENSMUSG00000038416


Mus musculus

Features
Gene ID: ENSMUSG00000038416
  
Biological name :Cdc16
  
Synonyms : Cdc16 / Cell division cycle / Q8R349
  
Possible biological names infered from orthology : cell division cycle 16 / Q13042
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A1.1
Gene start: 13757676
Gene end: 13781938
  
Corresponding Affymetrix probe sets: 10570397 (MoGene1.0st)   1425554_a_at (Mouse Genome 430 2.0 Array)   1431291_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000047950
Ensembl peptide - ENSMUSP00000147399
Ensembl peptide - ENSMUSP00000147594
NCBI entrez gene - 69957     See in Manteia.
MGI - MGI:1917207
RefSeq - XM_006508884
RefSeq - NM_027276
RefSeq - XM_006508882
RefSeq - XM_006508883
RefSeq Peptide - NP_081552
swissprot - Q3TZ92
swissprot - Q8R349
swissprot - A0A1B0GR68
swissprot - Q3TI84
Ensembl - ENSMUSG00000038416
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc16ENSDARG00000055470Danio rerio
 CDC16ENSGALG00000016816Gallus gallus
 CDC16ENSG00000130177Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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