ENSMUSG00000039057


Mus musculus

Features
Gene ID: ENSMUSG00000039057
  
Biological name :Myo16
  
Synonyms : Myo16 / Q5DU14 / Unconventional myosin-XVI
  
Possible biological names infered from orthology : myosin XVI / Q9Y6X6
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A1.1
Gene start: 10153911
Gene end: 10634742
  
Corresponding Affymetrix probe sets: 10570029 (MoGene1.0st)   1445532_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000049345
Ensembl peptide - ENSMUSP00000146796
Ensembl peptide - ENSMUSP00000147072
Ensembl peptide - ENSMUSP00000149384
Ensembl peptide - ENSMUSP00000146677
NCBI entrez gene - 244281     See in Manteia.
MGI - MGI:2685951
RefSeq - XM_006508780
RefSeq - NM_001319151
RefSeq - XM_006508778
RefSeq - XM_006508779
RefSeq Peptide - NP_001306080
swissprot - Q5DU14
swissprot - F8WGF8
swissprot - A0A1L1SRA7
swissprot - A0A140LJ46
Ensembl - ENSMUSG00000039057
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo16ENSDARG00000078582Danio rerio
 MYO16ENSGALG00000016837Gallus gallus
 MYO16ENSG00000041515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo3a / myosin-IIIa / Q8NEV4*ENSMUSG0000002571619
Myo3b / Q1EG27 / Myosin-IIIb / Q8WXR4*ENSMUSG0000004206418
Myo19 / Q5SV80 / Unconventional myosin-XIX / Q96H55* / myosin XIX*ENSMUSG0000002052711


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036042  Class XVI myosin, motor domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0008285 negative regulation of cell proliferation ISS
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IDA
 biological_processGO:0021549 cerebellum development ISS
 biological_processGO:0048812 neuron projection morphogenesis IDA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle ISS
 cellular_componentGO:0005654 nucleoplasm ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0002175 low brain weight "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
Show

Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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