ENSMUSG00000042064


Mus musculus

Features
Gene ID: ENSMUSG00000042064
  
Biological name :Myo3b
  
Synonyms : Myo3b / Myosin-IIIb / Q1EG27
  
Possible biological names infered from orthology : Q8WXR4
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C2
Gene start: 70039126
Gene end: 70429198
  
Corresponding Affymetrix probe sets: 10472649 (MoGene1.0st)   1459299_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055362
Ensembl peptide - ENSMUSP00000107860
Ensembl peptide - ENSMUSP00000107862
NCBI entrez gene - 329421     See in Manteia.
MGI - MGI:2448580
RefSeq - XM_017319045
RefSeq - NM_177376
RefSeq - XM_017319041
RefSeq - XM_017319042
RefSeq - XM_017319043
RefSeq - XM_017319044
RefSeq - XM_006499745
RefSeq - XM_006499750
RefSeq - XM_017319037
RefSeq - XM_017319038
RefSeq - XM_017319039
RefSeq - XM_017319040
RefSeq Peptide - NP_796350
swissprot - Q0P645
swissprot - Q1EG27
swissprot - F8VQ79
Ensembl - ENSMUSG00000042064
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo3bENSDARG00000006892Danio rerio
 MYO3BENSGALG00000009602Gallus gallus
 MYO3BENSG00000071909Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo3a / myosin-IIIa / Q8NEV4*ENSMUSG0000002571656
Myo16 / Q5DU14 / Unconventional myosin-XVI / Q9Y6X6* / myosin XVI*ENSMUSG0000003905726
Myo19 / Q5SV80 / Unconventional myosin-XIX / Q96H55* / myosin XIX*ENSMUSG0000002052718


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR000719  Protein kinase domain
 IPR001609  Myosin head, motor domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036083  Class III myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IPI
 biological_processGO:0090103 cochlea morphogenesis IMP
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0001917 photoreceptor inner segment IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0032420 stereocilium IEA
 cellular_componentGO:0032426 stereocilium tip IDA
 cellular_componentGO:0032433 filopodium tip IPI
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000146 microfilament motor activity IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000947 convulsive seizures "seizures characterized by uncontrolled motor activity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp

 MP:0011396 abnormal sleep behavior "any anomaly in the actions, reactions, or performance of an organism during a periodic, readily reversible state of reduced awareness and metabolic activity" [MGI:smb]
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Allelic Composition: Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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