ENSMUSG00000039158


Mus musculus

Features
Gene ID: ENSMUSG00000039158
  
Biological name :Akna
  
Synonyms : Akna / AT-hook-containing transcription factor / Q80VW7
  
Possible biological names infered from orthology : AT-hook transcription factor / Q7Z591
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: C1
Gene start: 63367125
Gene end: 63403354
  
Corresponding Affymetrix probe sets: 10513666 (MoGene1.0st)   1427325_s_at (Mouse Genome 430 2.0 Array)   1452393_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041614
NCBI entrez gene - 100182     See in Manteia.
MGI - MGI:2140340
RefSeq - XM_011249894
RefSeq - NM_001045514
RefSeq - NM_001305432
RefSeq - XM_006537520
RefSeq - XM_006537521
RefSeq - XM_006537522
RefSeq Peptide - NP_001292361
RefSeq Peptide - NP_001038979
swissprot - Q80VW7
Ensembl - ENSMUSG00000039158
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aknaENSDARG00000087110Danio rerio
 ENSGALG00000037031Gallus gallus
 AKNAENSG00000106948Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR022150  Transcription factor, AT-hook-containing


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0001650 fibrillar center IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0001861 lung inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the lung" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0005088 increased acute inflammation "greater than the expected early reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response " [Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0005399 increased susceptibility to fungal infection "greater likelihood that an organism will develop ill effects from infection by a yeast or mold, or from components of, or toxins produced by, these organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

Allelic Composition: Aknatm2Mak/Aknatm2Mak
Genetic Background: B6.129-Aknatm2Mak

 MP:0010922 alveolitis "inflammation of the small sac-like dilations of the distal airspace of the lung; acute pulmonary alveolitis involves exudate into the pulmonary alveoli and impaired gas exchange" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Sgtatm1.1Drmcr/Sgta+
Genetic Background: involves: C57BL/6

Allelic Composition: Aknatm2Mak/Aknatm2Mak
Genetic Background: B6.129-Aknatm2Mak

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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