ENSMUSG00000039286


Mus musculus

Features
Gene ID: ENSMUSG00000039286
  
Biological name :Fndc3b
  
Synonyms : Fndc3b / Mus musculus fibronectin type III domain containing 3B (Fndc3b), transcript variant 2, mRNA.
  
Possible biological names infered from orthology : fibronectin type III domain containing 3B / Q53EP0
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: A3
Gene start: 27416162
Gene end: 27711307
  
Corresponding Affymetrix probe sets: 10497548 (MoGene1.0st)   1433833_at (Mouse Genome 430 2.0 Array)   1452783_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141888
Ensembl peptide - ENSMUSP00000041495
Ensembl peptide - ENSMUSP00000141620
NCBI entrez gene - 72007     See in Manteia.
MGI - MGI:1919257
RefSeq - XM_017319738
RefSeq - XM_006535546
RefSeq - XM_006535547
RefSeq - XM_011249711
RefSeq - XM_011249712
RefSeq - NM_001356953
RefSeq - NM_173182
RefSeq - XM_006535541
RefSeq - XM_006535543
RefSeq - XM_006535544
RefSeq Peptide - NP_775274
RefSeq Peptide - NP_001343882
swissprot - A0A0R4J0H8
swissprot - A0A0A6YX88
Ensembl - ENSMUSG00000039286
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fndc3baENSDARG00000078179Danio rerio
 fndc3bbENSDARG00000062023Danio rerio
 FNDC3BENSGALG00000009222Gallus gallus
 FNDC3BENSG00000075420Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fndc3a / Q8BX90 / Fibronectin type-III domain-containing protein 3A / Q9Y2H6* / fibronectin type III domain containing 3A*ENSMUSG0000003348737
Q6DFV6 / Fndc3c1 / Fibronectin type III domain containing protein 3C1 ENSMUSG0000003373730
Fnd3c2ENSMUSG0000007301224


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Chrna7tm1Bay/Chrna7tm1Bay,Chrnb2tm1Mdb/Chrnb2tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0005076 abnormal cell differentiation "anomaly in the process whereby relatively unspecialized cells, e. g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism s life history" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Chrna7tm1Bay/Chrna7tm1Bay,Chrnb2tm1Mdb/Chrnb2tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Fndc3btm1Maim/Fndc3btm1Maim
Genetic Background: involves: 129S2/SvPas

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Chrna7tm1Bay/Chrna7tm1Bay,Chrnb2tm1Mdb/Chrnb2tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Chrna7tm1Bay/Chrna7tm1Bay,Chrnb2tm1Mdb/Chrnb2tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0011708 decreased fibroblast cell migration "reduced frequency of or less rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Chrna7tm1Bay/Chrna7tm1Bay,Chrnb2tm1Mdb/Chrnb2tm1Mdb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0020039 increased bone ossification "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597]
Show

Allelic Composition: Fndc3btm1Maim/Fndc3btm1Maim
Genetic Background: involves: 129S2/SvPas

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr